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National Institutes of Health addresses the science of diversity
National Institutes of Health addresses the science of diversity
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National Institutes of Health addresses the science of diversity

Valantine, Hannah A ; Francis S. Collins

Proceedings of the National Academy of Sciences - PNAS, 2015-10, Vol.112 (40), p.12240-12242 [Periódico revisado por pares]

United States: National Academy of Sciences

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Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
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Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

Hindorff, Lucia A ; Sethupathy, Praveen ; Junkins, Heather A ; Ramos, Erin M ; Mehta, Jayashri P ; Collins, Francis S ; Manolio, Teri A

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (23), p.9362-9367 [Periódico revisado por pares]

United States: National Academy of Sciences

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3
Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle
Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle
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Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle

Taylor, D. Leland ; Jackson, Anne U. ; Narisu, Narisu ; Hemani, Gibran ; Erdos, Michael R. ; Chines, Peter S. ; Swift, Amy ; Idol, Jackie ; Didion, John P. ; Welch, Ryan P. ; Kinnunen, Leena ; Saramies, Jouko ; Lakka, Timo A. ; Laakso, Markku ; Tuomilehto, Jaakko ; Parker, Stephen C. J. ; Koistinen, Heikki A. ; Smith, George Davey ; Boehnke, Michael ; Scott, Laura J. ; Birney, Ewan ; Collins, Francis S.

Proceedings of the National Academy of Sciences - PNAS, 2019-05, Vol.116 (22), p.10883-10888 [Periódico revisado por pares]

United States: National Academy of Sciences

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4
lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells
lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells
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lamin A protein isoform overexpressed in Hutchinson-Gilford progeria syndrome interferes with mitosis in progeria and normal cells

Cao, Kan ; Capell, Brian C ; Erdos, Michael R ; Djabali, Karima ; Collins, Francis S

Proceedings of the National Academy of Sciences - PNAS, 2007-03, Vol.104 (12), p.4949-4954 [Periódico revisado por pares]

United States: National Academy of Sciences

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5
Mutant Nuclear Lamin a Leads to Progressive Alterations of Epigenetic Control in Premature Aging
Mutant Nuclear Lamin a Leads to Progressive Alterations of Epigenetic Control in Premature Aging
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Mutant Nuclear Lamin a Leads to Progressive Alterations of Epigenetic Control in Premature Aging

Shumaker, Dale K. ; Dechat, Thomas ; Kohlmaier, Alexander ; Adam, Stephen A. ; Bozovsky, Matthew R. ; Erdos, Michael R. ; Eriksson, Maria ; Goldman, Anne E. ; Khuon, Satya ; Collins, Francis S. ; Jenuwein, Thomas ; Goldman, Robert D.

Proceedings of the National Academy of Sciences - PNAS, 2006-06, Vol.103 (23), p.8703-8708 [Periódico revisado por pares]

United States: National Academy of Sciences

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6
progeria mutation reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization
progeria mutation reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization
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progeria mutation reveals functions for lamin A in nuclear assembly, architecture, and chromosome organization

Taimen, Pekka ; Pfleghaar, Katrin ; Shimi, Takeshi ; Möller, Dorothee ; Ben-Harush, Kfir ; Erdos, Michael R ; Adam, Stephen A ; Herrmann, Harald ; Medalia, Ohad ; Collins, Francis S ; Goldman, Anne E ; Goldman, Robert D

Proceedings of the National Academy of Sciences - PNAS, 2009-12, Vol.106 (49), p.20788-20793 [Periódico revisado por pares]

United States: National Academy of Sciences

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7
Accumulation of Mutant Lamin A Causes Progressive Changes in Nuclear Architecture in Hutchinson-Gilford Progeria Syndrome
Accumulation of Mutant Lamin A Causes Progressive Changes in Nuclear Architecture in Hutchinson-Gilford Progeria Syndrome
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Accumulation of Mutant Lamin A Causes Progressive Changes in Nuclear Architecture in Hutchinson-Gilford Progeria Syndrome

Goldman, Robert D. ; Shumaker, Dale K. ; Erdos, Michael R. ; Eriksson, Maria ; Goldman, Anne E. ; Gordon, Leslie B. ; Gruenbaum, Yosef ; Khuon, Satya ; Mendez, Melissa ; Varga, Renée ; Collins, Francis S.

Proceedings of the National Academy of Sciences - PNAS, 2004-06, Vol.101 (24), p.8963-8968 [Periódico revisado por pares]

United States: National Academy of Sciences

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8
farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model
farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model
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farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model

Capell, Brian C ; Olive, Michelle ; Erdos, Michael R ; Cao, Kan ; Faddah, Dina A ; Tavarez, Urraca L ; Conneely, Karen N ; Qu, Xuan ; San, Hong ; Ganesh, Santhi K ; Chen, Xiaoyan ; Avallone, Hedwig ; Kolodgie, Frank D ; Virmani, Renu ; Nabel, Elizabeth G ; Collins, Francis S

Proceedings of the National Academy of Sciences - PNAS, 2008-10, Vol.105 (41), p.15902-15907 [Periódico revisado por pares]

United States: National Academy of Sciences

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9
Short Interfering RNAs Can Induce Unexpected and Divergent Changes in the Levels of Untargeted Proteins in Mammalian Cells
Short Interfering RNAs Can Induce Unexpected and Divergent Changes in the Levels of Untargeted Proteins in Mammalian Cells
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Short Interfering RNAs Can Induce Unexpected and Divergent Changes in the Levels of Untargeted Proteins in Mammalian Cells

Scacheri, Peter C. ; Rozenblatt-Rosen, Orit ; Caplen, Natasha J. ; Wolfsberg, Tyra G. ; Umayam, Lowell ; Lee, Jeffrey C. ; Hughes, Christina M. ; Shanmugam, Kalai Selvi ; Bhattacharjee, Arindam ; Meyerson, Matthew ; Collins, Francis S. ; Vogelstein, Bert

Proceedings of the National Academy of Sciences - PNAS, 2004-02, Vol.101 (7), p.1892-1897 [Periódico revisado por pares]

United States: National Academy of Sciences

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10
Inhibiting Farnesylation of Progerin Prevents the Characteristic Nuclear Blebbing of Hutchinson-Gilford Progeria Syndrome
Inhibiting Farnesylation of Progerin Prevents the Characteristic Nuclear Blebbing of Hutchinson-Gilford Progeria Syndrome
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Inhibiting Farnesylation of Progerin Prevents the Characteristic Nuclear Blebbing of Hutchinson-Gilford Progeria Syndrome

Capell, Brian C. ; Erdos, Michael R. ; Madigan, James P. ; Fiordalisi, James J. ; Varga, Renee ; Conneely, Karen N. ; Gordon, Leslie B. ; Der, Channing J. ; Cox, Adrienne D. ; Collins, Francis S.

Proceedings of the National Academy of Sciences - PNAS, 2005-09, Vol.102 (36), p.12879-12884 [Periódico revisado por pares]

United States: National Academy of Sciences

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