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1 |
Material Type: Artigo
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A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate CancerTakeda, David Y. ; Spisák, Sándor ; Seo, Ji-Heui ; Bell, Connor ; O’Connor, Edward ; Korthauer, Keegan ; Ribli, Dezső ; Csabai, István ; Solymosi, Norbert ; Szállási, Zoltán ; Stillman, David R. ; Cejas, Paloma ; Qiu, Xintao ; Long, Henry W. ; Tisza, Viktória ; Nuzzo, Pier Vitale ; Rohanizadegan, Mersedeh ; Pomerantz, Mark M. ; Hahn, William C. ; Freedman, Matthew L.Cell, 2018-07, Vol.174 (2), p.422-432.e13 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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The androgen receptor cistrome is extensively reprogrammed in human prostate tumorigenesisPomerantz, Mark M ; Li, Fugen ; Takeda, David Y ; Lenci, Romina ; Chonkar, Apurva ; Chabot, Matthew ; Cejas, Paloma ; Vazquez, Francisca ; Cook, Jennifer ; Shivdasani, Ramesh A ; Bowden, Michaela ; Lis, Rosina ; Hahn, William C ; Kantoff, Philip W ; Brown, Myles ; Loda, Massimo ; Long, Henry W ; Freedman, Matthew LNature genetics, 2015-11, Vol.47 (11), p.1346-1351 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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ASCL1 activates neuronal stem cell-like lineage programming through remodeling of the chromatin landscape in prostate cancerNouruzi, Shaghayegh ; Ganguli, Dwaipayan ; Tabrizian, Nakisa ; Kobelev, Maxim ; Sivak, Olena ; Namekawa, Takeshi ; Thaper, Daksh ; Baca, Sylvan C ; Freedman, Matthew L ; Aguda, Adeleke ; Davies, Alastair ; Zoubeidi, AminaNature communications, 2022-04, Vol.13 (1), p.2282-2282, Article 2282 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Androgen receptor and MYC equilibration centralizes on developmental super-enhancerGuo, Haiyang ; Wu, Yiming ; Nouri, Mannan ; Spisak, Sandor ; Russo, Joshua W ; Sowalsky, Adam G ; Pomerantz, Mark M ; Wei, Zhao ; Korthauer, Keegan ; Seo, Ji-Heui ; Wang, Liyang ; Arai, Seiji ; Freedman, Matthew L ; He, Housheng Hansen ; Chen, Shaoyong ; Balk, Steven PNature communications, 2021-12, Vol.12 (1), p.7308-7308, Article 7308 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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A transcriptome-wide association study of high-grade serous epithelial ovarian cancer identifies new susceptibility genes and splice variantsGusev, Alexander ; Lawrenson, Kate ; Lin, Xianzhi ; Lyra, Jr, Paulo C ; Kar, Siddhartha ; Vavra, Kevin C ; Segato, Felipe ; Fonseca, Marcos A S ; Lee, Janet M ; Pejovic, Tanya ; Liu, Gang ; Karlan, Beth Y ; Freedman, Matthew L ; Noushmehr, Houtan ; Monteiro, Alvaro N ; Pharoah, Paul D P ; Pasaniuc, Bogdan ; Gayther, Simon ANature genetics, 2019-05, Vol.51 (5), p.815-823 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Regulation of the glucocorticoid receptor via a BET-dependent enhancer drives antiandrogen resistance in prostate cancerShah, Neel ; Wang, Ping ; Wongvipat, John ; Karthaus, Wouter R ; Abida, Wassim ; Armenia, Joshua ; Rockowitz, Shira ; Drier, Yotam ; Bernstein, Bradley E ; Long, Henry W ; Freedman, Matthew L ; Arora, Vivek K ; Zheng, Deyou ; Sawyers, Charles LeLife, 2017-09, Vol.6 [Periódico revisado por pares]England: eLife Science Publications, LtdTexto completo disponível |
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Material Type: Artigo
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8q24 prostate, breast, and colon cancer risk loci show tissue-specific long-range interaction with MYCAhmadiyeh, Nasim ; Pomerantz, Mark M ; Grisanzio, Chiara ; Herman, Paula ; Jia, Li ; Almendro, Vanessa ; He, Housheng Hansen ; Brown, Myles ; Liu, X. Shirley ; Davis, Matt ; Caswell, Jennifer L ; Beckwith, Christine A ; Hills, Adam ; MacConaill, Laura ; Coetzee, Gerhard A ; Regan, Meredith M ; Freedman, Matthew LProceedings of the National Academy of Sciences - PNAS, 2010-05, Vol.107 (21), p.9742-9746 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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A rare variant of African ancestry activates 8q24 lncRNA hub by modulating cancer associated enhancerWalavalkar, Kaivalya ; Saravanan, Bharath ; Singh, Anurag Kumar ; Jayani, Ranveer Singh ; Nair, Ashwin ; Farooq, Umer ; Islam, Zubairul ; Soota, Deepanshu ; Mann, Rajat ; Shivaprasad, Padubidri V ; Freedman, Matthew L ; Sabarinathan, Radhakrishnan ; Haiman, Christopher A ; Notani, DimpleNature communications, 2020-07, Vol.11 (1), p.3598-3598, Article 3598 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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The PENGUIN approach to reconstruct protein interactions at enhancer-promoter regions and its application to prostate cancerArmaos, Alexandros ; Serra, François ; Núñez-Carpintero, Iker ; Seo, Ji-Heui ; Baca, Sylvan C ; Gustincich, Stefano ; Valencia, Alfonso ; Freedman, Matthew L ; Cirillo, Davide ; Giambartolomei, Claudia ; Tartaglia, Gian GaetanoNature communications, 2023-12, Vol.14 (1), p.8084-8084, Article 8084 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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A biallelic multiple nucleotide length polymorphism explains functional causality at 5p15.33 prostate cancer risk locusSpisak, Sandor ; Tisza, Viktoria ; Nuzzo, Pier Vitale ; Seo, Ji-Heui ; Pataki, Balint ; Ribli, Dezso ; Sztupinszki, Zsofia ; Bell, Connor ; Rohanizadegan, Mersedeh ; Stillman, David R ; Alaiwi, Sarah Abou ; Bartels, Alan H ; Papp, Marton ; Shetty, Anamay ; Abbasi, Forough ; Lin, Xianzhi ; Lawrenson, Kate ; Gayther, Simon A ; Pomerantz, Mark ; Baca, Sylvan ; Solymosi, Norbert ; Csabai, Istvan ; Szallasi, Zoltan ; Gusev, Alexander ; Freedman, Matthew LNature communications, 2023-08, Vol.14 (1), p.5118-5118, Article 5118 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |