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1
Improved Efficacy and Reduced Toxicity Using a Custom-Designed Irinotecan-Delivering Silicasome for Orthotopic Colon Cancer
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Improved Efficacy and Reduced Toxicity Using a Custom-Designed Irinotecan-Delivering Silicasome for Orthotopic Colon Cancer

Liu, Xiangsheng ; Jiang, Jinhong ; Chan, Ryan ; Ji, Ying ; Lu, Jianqin ; Liao, Yu-Pei ; Okene, Michael ; Lin, Joshua ; Lin, Paulina ; Chang, Chong Hyun ; Wang, Xiang ; Tang, Ivanna ; Zheng, Emily ; Qiu, Waveley ; Wainberg, Zev A ; Nel, Andre E ; Meng, Huan

ACS nano, 2019-01, Vol.13 (1), p.38-53 [Periódico revisado por pares]

United States: American Chemical Society

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2
Irinotecan-Still an Important Player in Cancer Chemotherapy: A Comprehensive Overview
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Artigo
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Irinotecan-Still an Important Player in Cancer Chemotherapy: A Comprehensive Overview

Kciuk, Mateusz ; Marciniak, Beata ; Kontek, Renata

International journal of molecular sciences, 2020-07, Vol.21 (14), p.4919 [Periódico revisado por pares]

Switzerland: MDPI AG

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3
Neoadjuvant chemotherapy with FOLFIRINOX and preoperative chemoradiotherapy for patients with locally advanced rectal cancer (UNICANCER-PRODIGE 23): a multicentre, randomised, open-label, phase 3 trial
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Neoadjuvant chemotherapy with FOLFIRINOX and preoperative chemoradiotherapy for patients with locally advanced rectal cancer (UNICANCER-PRODIGE 23): a multicentre, randomised, open-label, phase 3 trial

Conroy, Thierry ; Bosset, Jean-François ; Etienne, Pierre-Luc ; Rio, Emmanuel ; François, Éric ; Mesgouez-Nebout, Nathalie ; Vendrely, Véronique ; Artignan, Xavier ; Bouché, Olivier ; Gargot, Dany ; Boige, Valérie ; Bonichon-Lamichhane, Nathalie ; Louvet, Christophe ; Morand, Clotilde ; de la Fouchardière, Christelle ; Lamfichekh, Najib ; Juzyna, Béata ; Jouffroy-Zeller, Claire ; Rullier, Eric ; Marchal, Frédéric ; Gourgou, Sophie ; Castan, Florence ; Borg, Christophe ; Borg, Christophe ; Etienne, Pierre-Luc ; Rio, Emmanuel ; Mesgouez-Nebout, Nathalie ; François, Éric ; Vendrely, Véronique ; Conroy, Thierry ; Artignan, Xavier ; Bouché, Olivier ; Gargot, Dany ; Boige, Valérie ; Bonichon-Lamichhane, Nathalie ; Louvet, Christophe ; Morand, Clotilde ; de la Fouchardière, Christelle ; Ronchin, Philippe ; Seitz, Jean-François ; Corbinais, Stéphane ; Maillard, Emmanuel ; Noirclerc, Monique ; El Hajbi, Farid ; Villing, Anne-Laure ; Bécouarn, Yves ; Foong Fat Lam Kam Sang, Lam ; Artru, Pascal ; Bachet, Jean-Baptiste ; Hocine, Fayçal ; Ligeza-Poisson, Catherine ; Vautravers, Claire ; Ben Abdelghani, Meher ; Aparicio, Thomas ; Desot, Elise ; Marquis, Isabelle

The lancet oncology, 2021-05, Vol.22 (5), p.702-715 [Periódico revisado por pares]

England: Elsevier Ltd

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4
A multicenter retrospective observational NAPOLEON2 study of nanoliposomal irinotecan with fluorouracil and folinic acid in patients with unresectable pancreatic cancer
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Artigo
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A multicenter retrospective observational NAPOLEON2 study of nanoliposomal irinotecan with fluorouracil and folinic acid in patients with unresectable pancreatic cancer

Kodama, Tomoko ; Imajima, Takashi ; Shimokawa, Mototsugu ; Otsuka, Taiga ; Kawahira, Masahiro ; Nakazawa, Junichi ; Hori, Takeshi ; Shibuki, Taro ; Arima, Shiho ; Ido, Akio ; Miwa, Keisuke ; Okabe, Yoshinobu ; Koga, Futa ; Ueda, Yujiro ; Kubotsu, Yoshihito ; Shimokawa, Hozumi ; Takeshita, Shigeyuki ; Nishikawa, Kazuo ; Komori, Azusa ; Otsu, Satoshi ; Hosokawa, Ayumu ; Sakai, Tatsunori ; Sakai, Kenji ; Oda, Hisanobu ; Kawahira, Machiko ; Arita, Shuji ; Honda, Takuya ; Taguchi, Hiroki ; Tsuneyoshi, Kengo ; Kawaguchi, Yasunori ; Fujita, Toshihiro ; Sakae, Takahiro ; Shirakawa, Tsuyoshi ; Mizuta, Toshihiko ; Mitsugi, Kenji

Scientific reports, 2024-05, Vol.14 (1), p.12422-10, Article 12422 [Periódico revisado por pares]

England: Nature Publishing Group

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5
Bioanalytical method for the simultaneous quantification of irinotecan and its active metabolite SN-38 in mouse plasma and tissue homogenates using HPLC-fluorescence
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Artigo
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Bioanalytical method for the simultaneous quantification of irinotecan and its active metabolite SN-38 in mouse plasma and tissue homogenates using HPLC-fluorescence

Martínez-Chávez, Alejandra ; Rosing, Hilde ; Gan, Changpei ; Wang, Yaogeng ; Schinkel, Alfred H. ; Beijnen, Jos H.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2020-07, Vol.1149, p.122177, Article 122177 [Periódico revisado por pares]

Netherlands: Elsevier B.V

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6
Targeting Topoisomerase I in the Era of Precision Medicine
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Targeting Topoisomerase I in the Era of Precision Medicine

Thomas, Anish ; Pommier, Yves

Clinical cancer research, 2019-11, Vol.25 (22), p.6581-6589 [Periódico revisado por pares]

United States

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7
Blood-brain barrier disruption and delivery of irinotecan in a rat model using a clinical transcranial MRI-guided focused ultrasound system
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Artigo
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Blood-brain barrier disruption and delivery of irinotecan in a rat model using a clinical transcranial MRI-guided focused ultrasound system

McDannold, Nathan ; Zhang, Yongzhi ; Supko, Jeffrey G ; Power, Chanikarn ; Sun, Tao ; Vykhodtseva, Natalia ; Golby, Alexandra J ; Reardon, David A

Scientific reports, 2020-05, Vol.10 (1), p.8766-19, Article 8766 [Periódico revisado por pares]

England: Nature Publishing Group

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8
NAPOLI-1 phase 3 study of liposomal irinotecan in metastatic pancreatic cancer: Final overall survival analysis and characteristics of long-term survivors
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Artigo
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NAPOLI-1 phase 3 study of liposomal irinotecan in metastatic pancreatic cancer: Final overall survival analysis and characteristics of long-term survivors

Wang-Gillam, Andrea ; Hubner, Richard A. ; Siveke, Jens T. ; Von Hoff, Daniel D. ; Belanger, Bruce ; de Jong, Floris A. ; Mirakhur, Beloo ; Chen, Li-Tzong

European journal of cancer (1990), 2019-02, Vol.108, p.78-87 [Periódico revisado por pares]

England: Elsevier Ltd

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9
Prediction of irinotecan toxicity in metastatic colorectal cancer patients based on machine learning models with pharmacokinetic parameters
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Artigo
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Prediction of irinotecan toxicity in metastatic colorectal cancer patients based on machine learning models with pharmacokinetic parameters

Oyaga-Iriarte, Esther ; Insausti, Asier ; Sayar, Onintza ; Aldaz, Azucena

Journal of pharmacological sciences, 2019-05, Vol.140 (1), p.20-25 [Periódico revisado por pares]

Japan: Elsevier B.V

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10
Nanoliposomal irinotecan with fluorouracil for the treatment of advanced pancreatic cancer, a single institution experience
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Nanoliposomal irinotecan with fluorouracil for the treatment of advanced pancreatic cancer, a single institution experience

Glassman, Danielle C ; Palmaira, Randze L ; Covington, Christina M ; Desai, Avni M ; Ku, Geoffrey Y ; Li, Jia ; Harding, James J ; Varghese, Anna M ; O'Reilly, Eileen M ; Yu, Kenneth H

BMC cancer, 2018-06, Vol.18 (1), p.693-693, Article 693 [Periódico revisado por pares]

England: BioMed Central Ltd

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