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Material Type: Artigo
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Improved Efficacy and Reduced Toxicity Using a Custom-Designed Irinotecan-Delivering Silicasome for Orthotopic Colon CancerLiu, Xiangsheng ; Jiang, Jinhong ; Chan, Ryan ; Ji, Ying ; Lu, Jianqin ; Liao, Yu-Pei ; Okene, Michael ; Lin, Joshua ; Lin, Paulina ; Chang, Chong Hyun ; Wang, Xiang ; Tang, Ivanna ; Zheng, Emily ; Qiu, Waveley ; Wainberg, Zev A ; Nel, Andre E ; Meng, HuanACS nano, 2019-01, Vol.13 (1), p.38-53 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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Irinotecan-Still an Important Player in Cancer Chemotherapy: A Comprehensive OverviewKciuk, Mateusz ; Marciniak, Beata ; Kontek, RenataInternational journal of molecular sciences, 2020-07, Vol.21 (14), p.4919 [Periódico revisado por pares]Switzerland: MDPI AGTexto completo disponível |
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Neoadjuvant chemotherapy with FOLFIRINOX and preoperative chemoradiotherapy for patients with locally advanced rectal cancer (UNICANCER-PRODIGE 23): a multicentre, randomised, open-label, phase 3 trialConroy, Thierry ; Bosset, Jean-François ; Etienne, Pierre-Luc ; Rio, Emmanuel ; François, Éric ; Mesgouez-Nebout, Nathalie ; Vendrely, Véronique ; Artignan, Xavier ; Bouché, Olivier ; Gargot, Dany ; Boige, Valérie ; Bonichon-Lamichhane, Nathalie ; Louvet, Christophe ; Morand, Clotilde ; de la Fouchardière, Christelle ; Lamfichekh, Najib ; Juzyna, Béata ; Jouffroy-Zeller, Claire ; Rullier, Eric ; Marchal, Frédéric ; Gourgou, Sophie ; Castan, Florence ; Borg, Christophe ; Borg, Christophe ; Etienne, Pierre-Luc ; Rio, Emmanuel ; Mesgouez-Nebout, Nathalie ; François, Éric ; Vendrely, Véronique ; Conroy, Thierry ; Artignan, Xavier ; Bouché, Olivier ; Gargot, Dany ; Boige, Valérie ; Bonichon-Lamichhane, Nathalie ; Louvet, Christophe ; Morand, Clotilde ; de la Fouchardière, Christelle ; Ronchin, Philippe ; Seitz, Jean-François ; Corbinais, Stéphane ; Maillard, Emmanuel ; Noirclerc, Monique ; El Hajbi, Farid ; Villing, Anne-Laure ; Bécouarn, Yves ; Foong Fat Lam Kam Sang, Lam ; Artru, Pascal ; Bachet, Jean-Baptiste ; Hocine, Fayçal ; Ligeza-Poisson, Catherine ; Vautravers, Claire ; Ben Abdelghani, Meher ; Aparicio, Thomas ; Desot, Elise ; Marquis, IsabelleThe lancet oncology, 2021-05, Vol.22 (5), p.702-715 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Prediction of irinotecan toxicity in metastatic colorectal cancer patients based on machine learning models with pharmacokinetic parametersOyaga-Iriarte, Esther ; Insausti, Asier ; Sayar, Onintza ; Aldaz, AzucenaJournal of pharmacological sciences, 2019-05, Vol.140 (1), p.20-25 [Periódico revisado por pares]Japan: Elsevier B.VTexto completo disponível |
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Material Type: Artigo
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SENP1 participates in Irinotecan resistance in human colon cancer cellsChen, Ming‐Cheng ; Nhan, Do Chi ; Hsu, Chiung‐Hung ; Wang, Tso‐Fu ; Li, Chi‐Cheng ; Ho, Tsung‐Jung ; Mahalakshmi, B. ; Chen, Mei‐Chih ; Yang, Liang‐Yo ; Huang, Chih‐YangJournal of cellular biochemistry, 2021-10, Vol.122 (10), p.1277-1294 [Periódico revisado por pares]United States: Wiley Subscription Services, IncTexto completo disponível |
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Material Type: Artigo
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Encorafenib, Binimetinib, and Cetuximab in BRAF V600E–Mutated Colorectal CancerKopetz, Scott ; Grothey, Axel ; Yaeger, Rona ; Van Cutsem, Eric ; Desai, Jayesh ; Yoshino, Takayuki ; Wasan, Harpreet ; Ciardiello, Fortunato ; Loupakis, Fotios ; Hong, Yong Sang ; Steeghs, Neeltje ; Guren, Tormod K ; Arkenau, Hendrik-Tobias ; Garcia-Alfonso, Pilar ; Pfeiffer, Per ; Orlov, Sergey ; Lonardi, Sara ; Elez, Elena ; Kim, Tae-Won ; Schellens, Jan H.M ; Guo, Christina ; Krishnan, Asha ; Dekervel, Jeroen ; Morris, Van ; Calvo Ferrandiz, Aitana ; Tarpgaard, L.S ; Braun, Michael ; Gollerkeri, Ashwin ; Keir, Christopher ; Maharry, Kati ; Pickard, Michael ; Christy-Bittel, Janna ; Anderson, Lisa ; Sandor, Victor ; Tabernero, JosepThe New England journal of medicine, 2019-10, Vol.381 (17), p.1632-1643 [Periódico revisado por pares]United States: Massachusetts Medical SocietyTexto completo disponível |
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Material Type: Artigo
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A phase II study of NK012, a polymeric micelle formulation of SN-38, in unresectable, metastatic or recurrent colorectal cancer patientsHamaguchi, Tetsuya ; Tsuji, Akihito ; Yamaguchi, Kensei ; Takeda, Koji ; Uetake, Hiroyuki ; Esaki, Taito ; Amagai, Kenji ; Sakai, Daisuke ; Baba, Hideo ; Kimura, Masami ; Matsumura, Yasuhiro ; Tsukamoto, TetsujiCancer chemotherapy and pharmacology, 2018-12, Vol.82 (6), p.1021-1029 [Periódico revisado por pares]Berlin/Heidelberg: Springer Berlin HeidelbergTexto completo disponível |
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Material Type: Artigo
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Colorectal Cancer Cells Enter a Diapause-like DTP State to Survive ChemotherapyRehman, Sumaiyah K. ; Haynes, Jennifer ; Collignon, Evelyne ; Brown, Kevin R. ; Wang, Yadong ; Nixon, Allison M.L. ; Bruce, Jeffrey P. ; Wintersinger, Jeffrey A. ; Singh Mer, Arvind ; Lo, Edwyn B.L. ; Leung, Cherry ; Lima-Fernandes, Evelyne ; Pedley, Nicholas M. ; Soares, Fraser ; McGibbon, Sophie ; He, Housheng Hansen ; Pollet, Aaron ; Pugh, Trevor J. ; Haibe-Kains, Benjamin ; Morris, Quaid ; Ramalho-Santos, Miguel ; Goyal, Sidhartha ; Moffat, Jason ; O’Brien, Catherine A.Cell, 2021-01, Vol.184 (1), p.226-242.e21 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Effect of drug metabolizing enzymes and transporters in Thai colorectal cancer patients treated with irinotecan-based chemotherapyAtasilp, Chalirmporn ; Chansriwong, Phichai ; Sirachainan, Ekaphop ; Reungwetwattana, Thanyanan ; Sirilerttrakul, Suwannee ; Chamnanphon, Monpat ; Puangpetch, Apichaya ; Sukasem, ChonlaphatScientific reports, 2020-08, Vol.10 (1), p.13486, Article 13486 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Systemic chemotherapy with or without cetuximab in patients with resectable colorectal liver metastasis (New EPOC): long-term results of a multicentre, randomised, controlled, phase 3 trialBridgewater, John A ; Pugh, Siân A ; Maishman, Tom ; Eminton, Zina ; Mellor, Jane ; Whitehead, Amy ; Stanton, Louise ; Radford, Michael ; Corkhill, Andrea ; Griffiths, Gareth O ; Falk, Stephen ; Valle, Juan W ; O'Reilly, Derek ; Siriwardena, Ajith K ; Hornbuckle, Joanne ; Rees, Myrddin ; Iveson, Timothy J ; Hickish, Tamas ; Garden, O James ; Cunningham, David ; Maughan, Timothy S ; Primrose, John N ; Shablack, Alaaeldin ; O'Callaghan, Ann ; Moody, (Margaret) Anne ; Allen, Alex ; Brewster, Alison ; Brown, Alison ; Mayer, Astrid ; Davidson, Brian ; Ton, Chan ; Wilson, Charles ; Lowdell, Charles ; Rees, Charlotte ; Baughan, Christopher ; Barlow, Clare ; Purcell, Colin ; Smith, David ; Tsang, David ; Brown, Ewan ; Walker, Georgina ; Malik, Hassan ; Cameron, Iain ; Nolan, Luke ; Hall, Marcia ; Tomlinson, Marjorie ; Hill, Mark ; Peterson, Mark ; Finch-Jones, Meg ; Kumar, Nagappan ; Karanjia, Nariman ; Ali, Nasim ; Heaton, Nigel ; Ton, Nua Chan ; Ross, Paul ; Praseedom, Raaj ; Thomas, Robert ; Clive, Sally ; Slater, Sarah ; Smith, Sarah ; Mudan, Satvinder ; Bhattacharya, Satya ; Essapen, Sharadah ; Raouf, Sherif ; Fenwick, Stephen ; Cleator, Susan ; Diamond, Tom ; Potter, VanessaThe lancet oncology, 2020-03, Vol.21 (3), p.398-411 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |