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1 |
Material Type: Artigo
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6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: Synthesis, structural studies and cytotoxic activitiesAmiable, Claire ; Paoletti, Julie ; Haouz, Ahmed ; Padilla, André ; Labesse, Gilles ; Kaminski, Pierre-Alexandre ; Pochet, SylvieEuropean journal of medicinal chemistry, 2014-10, Vol.85, p.418-437 [Periódico revisado por pares]France: Elsevier Masson SASTexto completo disponível |
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Material Type: Artigo
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Beyond directed evolution—semi-rational protein engineering and designLutz, StefanCurrent opinion in biotechnology, 2010-12, Vol.21 (6), p.734-743 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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In vitro cytotoxicity evaluation of some substituted isatin derivativesVine, Kara L. ; Locke, Julie M. ; Ranson, Marie ; Pyne, Stephen G. ; Bremner, John B.Bioorganic & medicinal chemistry, 2007-01, Vol.15 (2), p.931-938 [Periódico revisado por pares]England: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Increased Diels-Alderase activity through backbone remodeling guided by Foldit playersEIBEN, Christopher B ; SIEGEL, Justin B ; BALE, Jacob B ; COOPER, Seth ; KHATIB, Firas ; SHEN, Betty W ; PLAYERS, Foldit ; STODDARD, Barry L ; POPOVIC, Zoran ; BAKER, DavidNature biotechnology, 2012-02, Vol.30 (2), p.190-192 [Periódico revisado por pares]New York, NY: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Large-Scale Recombinant Expression and Purification of Human Tyrosinase Suitable for Structural StudiesLai, Xuelei ; Soler-Lopez, Montserrat ; Wichers, Harry J ; Dijkstra, Bauke W Oberer, MonikaPloS one, 2016-08, Vol.11 (8), p.e0161697-e0161697 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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Three-chain insulin analogs demonstrate the importance of insulin secondary structure to bioactivityWu, Fangzhou ; Chabenne, Joseph R. ; Gelfanov, Vasily M. ; Mayer, John P. ; DiMarchi, Richard D.Journal of peptide science, 2015-03, Vol.21 (3), p.223-230 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
7 |
Material Type: Artigo
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Second-generation sulfonamide inhibitors of d-glutamic acid-adding enzyme: Activity optimisation with conformationally rigid analogues of d-glutamic acidSosič, Izidor ; Barreteau, Hélène ; Simčič, Mihael ; Šink, Roman ; Cesar, Jožko ; Zega, Anamarija ; Grdadolnik, Simona Golič ; Contreras-Martel, Carlos ; Dessen, Andréa ; Amoroso, Ana ; Joris, Bernard ; Blanot, Didier ; Gobec, StanislavEuropean journal of medicinal chemistry, 2011-07, Vol.46 (7), p.2880-2894 [Periódico revisado por pares]Kidlington: Elsevier Masson SASTexto completo disponível |
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Material Type: Artigo
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Coumarin: A Natural, Privileged and Versatile Scaffold for Bioactive CompoundsStefanachi, Angela ; Leonetti, Francesco ; Pisani, Leonardo ; Catto, Marco ; Carotti, AngeloMolecules (Basel, Switzerland), 2018-01, Vol.23 (2), p.250 [Periódico revisado por pares]Switzerland: MDPI AGTexto completo disponível |
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Material Type: Artigo
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Inhibition of SARS-CoV 3CL protease by flavonoidsJo, Seri ; Kim, Suwon ; Shin, Dong Hae ; Kim, Mi-SunJournal of enzyme inhibition and medicinal chemistry, 2020-01, Vol.35 (1), p.145-151 [Periódico revisado por pares]England: Taylor & FrancisTexto completo disponível |
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Material Type: Artigo
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De novo Design of Catalytic ProteinsKaplan, J. ; DeGrado, W. F.Proceedings of the National Academy of Sciences - PNAS, 2004-08, Vol.101 (32), p.11566-11570 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |