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1 |
Material Type: Artigo
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Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulationShi, Hubing ; Sazegar, Hooman ; Nazarian, Ramin ; Chodon, Thinle ; Lee, Hane ; Sosman, Jeffrey A ; Lo, Roger S ; Koya, Richard C ; Lee, Mi-Kyung ; Attar, Narsis ; Kong, Xiangju ; Nelson, Stanley F ; Ribas, Antoni ; Chen, Zugen ; McArthur, Grant ; Wang, QiNature (London), 2010-12, Vol.468 (7326), p.973-977 [Periódico revisado por pares]London: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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COT drives resistance to RAF inhibition through MAP kinase pathway reactivationEmery, Caroline M ; Hieronymus, Haley ; Zhao, Jean J ; Boehm, Jesse S ; Golub, Todd ; Yang, Xiaoping ; Root, David E ; Roberts, Thomas M ; Hahn, William C ; Hill, David E ; Wilson, Christopher J ; Weber, Barbara L ; Garraway, Levi A ; Johnson, Laura A ; Kim, Sungjoon ; Harris, Jennifer L ; Kim, So Young ; Vidal, Marc ; Finan, Peter M ; Myer, Vic E ; Sellers, William R ; Barretina, Jordi ; Alkan, Ozan ; Thomas, Sapana R ; Wardwell, Leslie ; Cogdill, Alexandria P ; Dummer, Reinhard ; Schlegel, Robert ; Stransky, Nicolas ; Flaherty, Keith T ; Wargo, Jennifer A ; Murray, Ryan R ; Johannessen, Cory M ; Salehi-Ashtiani, Kourosh ; Caponigro, GiordanoNature (London), 2010-12, Vol.468 (7326), p.968-972 [Periódico revisado por pares]London: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Calcium channel blocker overdose mimicking an acute myocardial infarctionHenrikson, Charles A. ; Chandra-Strobos, NishaResuscitation, 2003-12, Vol.59 (3), p.361-364 [Periódico revisado por pares]Shannon: Elsevier Ireland LtdTexto completo disponível |
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Material Type: Artigo
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Secukinumab in Plaque Psoriasis — Results of Two Phase 3 TrialsLangley, Richard G ; Elewski, Boni E ; Lebwohl, Mark ; Reich, Kristian ; Griffiths, Christopher E.M ; Papp, Kim ; Puig, Lluís ; Nakagawa, Hidemi ; Spelman, Lynda ; Sigurgeirsson, Bárður ; Rivas, Enrique ; Tsai, Tsen-Fang ; Wasel, Norman ; Tyring, Stephen ; Salko, Thomas ; Hampele, Isabelle ; Notter, Marianne ; Karpov, Alexander ; Helou, Silvia ; Papavassilis, CharisThe New England journal of medicine, 2014-07, Vol.371 (4), p.326-338 [Periódico revisado por pares]Waltham, MA: Massachusetts Medical SocietyTexto completo disponível |
5 |
Material Type: Livro
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Drugs Looking for Diseases: Innovative Drug Research and the Development of the Beta Blockers and the Calcium AntagonistsVos, RDordrecht: Springer Netherlands 1990Texto completo disponível |
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Material Type: Artigo
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Goitrogens in food and waterGaitan, E. (University of Mississippi School of Medicine, Jackson, MS)Annual review of nutrition, 1990-01, Vol.10 (1), p.21-39 [Periódico revisado por pares]Palo Alto, CA: Annual ReviewsTexto completo disponível |
7 |
Material Type: Artigo
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Docosahexaenoic acid (DHA) has neuroprotective effects against oxidative stress in retinal ganglion cellsShimazawa, Masamitsu ; Nakajima, Yoshimi ; Mashima, Yukihiko ; Hara, HideakiBrain research, 2009-01, Vol.1251, p.269-275 [Periódico revisado por pares]Amsterdam: Elsevier B.VTexto completo disponível |
8 |
Material Type: Artigo
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IN VITRO CHARACTERIZATION OF CLOBAZAM METABOLISM BY RECOMBINANT CYTOCHROME P450 ENZYMES: IMPORTANCE OF CYP2C19GIRAUD, Carole ; TRAN, Agnès ; REY, Elisabeth ; VINCENT, Jean ; TRELUYER, Jean-Marc ; PONS, GérardDrug metabolism and disposition, 2004-11, Vol.32 (11), p.1279-1286 [Periódico revisado por pares]Bethesda, MD: American Society for Pharmacology and Experimental TherapeuticsTexto completo disponível |
9 |
Material Type: Artigo
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Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivoABBAS, Atheir I ; HEDLUND, Peter B ; HUANG, Xi-Ping ; TRAN, Thuy B ; MELTZER, Herbert Y ; ROTH, Bryan LPsychopharmacologia, 2009-07, Vol.205 (1), p.119-128 [Periódico revisado por pares]Berlin: SpringerTexto completo disponível |
10 |
Material Type: Artigo
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Frondoside A inhibits breast cancer metastasis and antagonizes prostaglandin E receptors EP4 and EP2Ma, Xinrong ; Kundu, Namita ; Collin, Peter D. ; Goloubeva, Olga ; Fulton, Amy M.Breast cancer research and treatment, 2012-04, Vol.132 (3), p.1001-1008 [Periódico revisado por pares]Boston: Springer USTexto completo disponível |