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CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas
CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas
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CCR2 inhibition reduces tumor myeloid cells and unmasks a checkpoint inhibitor effect to slow progression of resistant murine gliomas

Flores-Toro, Joseph A. ; Luo, Defang ; Gopinath, Adithya ; Sarkisian, Matthew R. ; Campbell, James J. ; Charo, Israel F. ; Singh, Rajinder ; Schall, Thomas J. ; Datta, Meenal ; Jain, Rakesh K. ; Mitchell, Duane A. ; Harrison, Jeffrey K.

Proceedings of the National Academy of Sciences - PNAS, 2020-01, Vol.117 (2), p.1129-1138 [Periódico revisado por pares]

United States: National Academy of Sciences

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2
Development of Monocytes, Macrophages, and Dendritic Cells
Development of Monocytes, Macrophages, and Dendritic Cells
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Development of Monocytes, Macrophages, and Dendritic Cells

Geissmann, Frederic ; Manz, Markus G ; Jung, Steffen ; Sieweke, Michael H ; Merad, Miriam ; Ley, Klaus

Science (American Association for the Advancement of Science), 2010-02, Vol.327 (5966), p.656-661 [Periódico revisado por pares]

Washington, DC: American Association for the Advancement of Science

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3
Cell-programmed nutrient partitioning in the tumour microenvironment
Cell-programmed nutrient partitioning in the tumour microenvironment
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Cell-programmed nutrient partitioning in the tumour microenvironment

Reinfeld, Bradley I ; Madden, Matthew Z ; Wolf, Melissa M ; Chytil, Anna ; Bader, Jackie E ; Patterson, Andrew R ; Sugiura, Ayaka ; Cohen, Allison S ; Ali, Ahmed ; Do, Brian T ; Muir, Alexander ; Lewis, Caroline A ; Hongo, Rachel A ; Young, Kirsten L ; Brown, Rachel E ; Todd, Vera M ; Huffstater, Tessa ; Abraham, Abin ; O'Neil, Richard T ; Wilson, Matthew H ; Xin, Fuxue ; Tantawy, M Noor ; Merryman, W David ; Johnson, Rachelle W ; Williams, Christopher S ; Mason, Emily F ; Mason, Frank M ; Beckermann, Katherine E ; Vander Heiden, Matthew G ; Manning, H Charles ; Rathmell, Jeffrey C ; Rathmell, W Kimryn

Nature (London), 2021-05, Vol.593 (7858), p.282-288 [Periódico revisado por pares]

England: Nature Publishing Group

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4
Association of COVID-19 inflammation with activation of the C5a-C5aR1 axis
Association of COVID-19 inflammation with activation of the C5a-C5aR1 axis
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Association of COVID-19 inflammation with activation of the C5a-C5aR1 axis

Carvelli, Julien ; Demaria, Olivier ; Vély, Frédéric ; Batista, Luciana ; Chouaki Benmansour, Nassima ; Fares, Joanna ; Carpentier, Sabrina ; Thibult, Marie-Laure ; Morel, Ariane ; Remark, Romain ; André, Pascale ; Represa, Agnès ; Piperoglou, Christelle ; Cordier, Pierre Yves ; Le Dault, Erwan ; Guervilly, Christophe ; Simeone, Pierre ; Gainnier, Marc ; Morel, Yannis ; Ebbo, Mikael ; Schleinitz, Nicolas ; Vivier, Eric

Nature (London), 2020-12, Vol.588 (7836), p.146-150 [Periódico revisado por pares]

England: Nature Publishing Group

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5
Porphyromonas gingivalis Promotes Colorectal Carcinoma by Activating the Hematopoietic NLRP3 Inflammasome
Porphyromonas gingivalis Promotes Colorectal Carcinoma by Activating the Hematopoietic NLRP3 Inflammasome
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Porphyromonas gingivalis Promotes Colorectal Carcinoma by Activating the Hematopoietic NLRP3 Inflammasome

Wang, Xi ; Jia, Yiqun ; Wen, Liling ; Mu, Wenxin ; Wu, Xianrui ; Liu, Tao ; Liu, Xiangqi ; Fang, Juan ; Luan, Yizhao ; Chen, Ping ; Gao, Jinlong ; Nguyen, Ky-Anh ; Cui, Jun ; Zeng, Gucheng ; Lan, Ping ; Chen, Qianming ; Cheng, Bin ; Wang, Zhi

Cancer research (Chicago, Ill.), 2021-05, Vol.81 (10), p.2745-2759 [Periódico revisado por pares]

United States

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6
Therapeutic targeting of tumor-associated myeloid cells synergizes with radiation therapy for glioblastoma
Therapeutic targeting of tumor-associated myeloid cells synergizes with radiation therapy for glioblastoma
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Therapeutic targeting of tumor-associated myeloid cells synergizes with radiation therapy for glioblastoma

Zhang, Peng ; Miska, Jason ; Lee-Chang, Catalina ; Rashidi, Aida ; Panek, Wojciech K. ; An, Shejuan ; Zannikou, Markella ; Lopez-Rosas, Aurora ; Han, Yu ; Xiao, Ting ; Pituch, Katarzyna C. ; Kanojia, Deepak ; Balyasnikova, Irina V. ; Lesniak, Maciej S.

Proceedings of the National Academy of Sciences - PNAS, 2019-11, Vol.116 (47), p.23714-23723 [Periódico revisado por pares]

United States: National Academy of Sciences

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7
The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models
The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models
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The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer models

Kotschy, András ; Szlavik, Zoltán ; Murray, James ; Davidson, James ; Maragno, Ana Leticia ; Le Toumelin-Braizat, Gaëtane ; Chanrion, Maïa ; Kelly, Gemma L ; Gong, Jia-Nan ; Moujalled, Donia M ; Bruno, Alain ; Csekei, Márton ; Paczal, Attila ; Szabo, Zoltán B ; Sipos, Szabolcs ; Radics, Gábor ; Proszenyak, Agnes ; Balint, Balázs ; Ondi, Levente ; Blasko, Gábor ; Robertson, Alan ; Surgenor, Allan ; Dokurno, Pawel ; Chen, Ijen ; Matassova, Natalia ; Smith, Julia ; Pedder, Christopher ; Graham, Christopher ; Studeny, Aurélie ; Lysiak-Auvity, Gaëlle ; Girard, Anne-Marie ; Gravé, Fabienne ; Segal, David ; Riffkin, Chris D ; Pomilio, Giovanna ; Galbraith, Laura C A ; Aubrey, Brandon J ; Brennan, Margs S ; Herold, Marco J ; Chang, Catherine ; Guasconi, Ghislaine ; Cauquil, Nicolas ; Melchiore, Fabien ; Guigal-Stephan, Nolwen ; Lockhart, Brian ; Colland, Frédéric ; Hickman, John A ; Roberts, Andrew W ; Huang, David C S ; Wei, Andrew H ; Strasser, Andreas ; Lessene, Guillaume ; Geneste, Olivier

Nature (London), 2016-10, Vol.538 (7626), p.477-482 [Periódico revisado por pares]

England: Nature Publishing Group

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8
Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia
Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia
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Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia

Powell, Jason A. ; Lewis, Alexander C. ; Zhu, Wenying ; Toubia, John ; Pitman, Melissa R. ; Wallington-Beddoe, Craig T. ; Moretti, Paul A.B. ; Iarossi, Diana ; Samaraweera, Saumya E. ; Cummings, Nik ; Ramshaw, Hayley S. ; Thomas, Daniel ; Wei, Andrew H. ; Lopez, Angel F. ; D'Andrea, Richard J. ; Lewis, Ian D. ; Pitson, Stuart M.

Blood, 2017-02, Vol.129 (6), p.771-782 [Periódico revisado por pares]

United States: Elsevier Inc

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9
Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans
Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans
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Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans

Arunachalam, Prabhu S ; Wimmers, Florian ; Mok, Chris Ka Pun ; Perera, Ranawaka A P M ; Scott, Madeleine ; Hagan, Thomas ; Sigal, Natalia ; Feng, Yupeng ; Bristow, Laurel ; Tak-Yin Tsang, Owen ; Wagh, Dhananjay ; Coller, John ; Pellegrini, Kathryn L ; Kazmin, Dmitri ; Alaaeddine, Ghina ; Leung, Wai Shing ; Chan, Jacky Man Chun ; Chik, Thomas Shiu Hong ; Choi, Chris Yau Chung ; Huerta, Christopher ; Paine McCullough, Michele ; Lv, Huibin ; Anderson, Evan ; Edupuganti, Srilatha ; Upadhyay, Amit A ; Bosinger, Steve E ; Maecker, Holden Terry ; Khatri, Purvesh ; Rouphael, Nadine ; Peiris, Malik ; Pulendran, Bali

Science (American Association for the Advancement of Science), 2020-09, Vol.369 (6508), p.1210-1220 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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10
Discovery of a first-in-class CDK2 selective degrader for AML differentiation therapy
Discovery of a first-in-class CDK2 selective degrader for AML differentiation therapy
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Discovery of a first-in-class CDK2 selective degrader for AML differentiation therapy

Wang, Liguo ; Shao, Xuejing ; Zhong, Tianbai ; Wu, Yue ; Xu, Aixiao ; Sun, Xiuyun ; Gao, Hongying ; Liu, Yongbo ; Lan, Tianlong ; Tong, Yan ; Tao, Xue ; Du, Wenxin ; Wang, Wei ; Chen, Yingqian ; Li, Ting ; Meng, Xianbin ; Deng, Haiteng ; Yang, Bo ; He, Qiaojun ; Ying, Meidan ; Rao, Yu

Nature chemical biology, 2021-05, Vol.17 (5), p.567-575 [Periódico revisado por pares]

United States: Nature Publishing Group

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