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Material Type: Artigo
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Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug BindingAller, Stephen G ; Yu, Jodie ; Ward, Andrew ; Weng, Yue ; Chittaboina, Srinivas ; Zhuo, Rupeng ; Harrell, Patina M ; Trinh, Yenphuong T ; Zhang, Qinghai ; Urbatsch, Ina L ; Chang, GeoffreyScience (American Association for the Advancement of Science), 2009-03, Vol.323 (5922), p.1718-1722 [Periódico revisado por pares]Washington, DC: American Association for the Advancement of ScienceTexto completo disponível |
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CD30 Downregulation, MMAE Resistance, and MDR1 Upregulation Are All Associated with Resistance to Brentuximab VedotinChen, Robert ; Hou, Jessie ; Newman, Edward ; Kim, Young ; Donohue, Cecile ; Liu, Xueli ; Thomas, Sandra H ; Forman, Stephen J ; Kane, Susan EMolecular cancer therapeutics, 2015-06, Vol.14 (6), p.1376-1384 [Periódico revisado por pares]United StatesTexto completo disponível |
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Blood-brain barrier P-glycoprotein function in Alzheimer's diseasevan Assema, Daniëlle M. E ; Lubberink, Mark ; Bauer, Martin ; van der Flier, Wiesje M ; Schuit, Robert C ; Windhorst, Albert D ; Comans, Emile F. I ; Hoetjes, Nikie J ; Tolboom, Nelleke ; Langer, Oliver ; Müller, Markus ; Scheltens, Philip ; Lammertsma, Adriaan A ; van Berckel, Bart N. MBrain (London, England : 1878), 2012-01, Vol.135 (1), p.181-189 [Periódico revisado por pares]Oxford: Oxford University PressTexto completo disponível |
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In vitro and in vivo P-glycoprotein transport characteristics of rivaroxabanGnoth, Mark Jean ; Buetehorn, Ulf ; Muenster, Uwe ; Schwarz, Thomas ; Sandmann, SteffenThe Journal of pharmacology and experimental therapeutics, 2011-07, Vol.338 (1), p.372-380 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Apatinib (YN968D1) Reverses Multidrug Resistance by inhibiting the Efflux Function of Multiple ATP-Binding Cassette TransportersMI, Yan-Jun ; LIANG, Yong-Ju ; MA, Xiao-Xu ; TO, Kenneth Kin Wah ; AMBUDKAR, Suresh V ; CHEN, Zhe-Sheng ; FU, Li-Wu ; HUANG, Hong-Bing ; ZHAO, Hong-Yun ; WU, Chung-Pu ; FANG WANG ; TAO, Li-Yang ; ZHANG, Chuan-Zhao ; DAI, Chun-Ling ; TIWARI, Amit KCancer research (Chicago, Ill.), 2010-10, Vol.70 (20), p.7981-7991 [Periódico revisado por pares]Philadelphia, PA: American Association for Cancer ResearchTexto completo disponível |
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Material Type: Artigo
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A "Silent" Polymorphism in the MDR1 Gene Changes Substrate SpecificityKimchi-Sarfaty, Chava ; Oh, Jung Mi ; Kim, In-Wha ; Sauna, Zuben E. ; Calcagno, Anna Maria ; Ambudkar, Suresh V. ; Gottesman, Michael M.Science (American Association for the Advancement of Science), 2007-01, Vol.315 (5811), p.525-528 [Periódico revisado por pares]Washington, DC: American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Species Differences in Blood-Brain Barrier Transport of Three Positron Emission Tomography Radioligands with Emphasis on P-Glycoprotein TransportSyvänen, Stina ; Lindhe, Orjan ; Palner, Mikael ; Kornum, Birgitte R ; Rahman, Obaidur ; Långström, Bengt ; Knudsen, Gitte M ; Hammarlund-Udenaes, MargaretaDrug metabolism and disposition, 2009-03, Vol.37 (3), p.635-643 [Periódico revisado por pares]Bethesda, MD: American Society for Pharmacology and Experimental TherapeuticsTexto completo disponível |
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Material Type: Artigo
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ABCB5 Maintains Melanoma-Initiating Cells through a Proinflammatory Cytokine Signaling CircuitWILSON, Brian J ; SAAB, Karim R ; FRANK, Markus H ; JIE MA ; SCHATTON, Tobias ; PÜTZ, Pablo ; QIAN ZHAN ; MURPHY, George F ; GASSER, Martin ; WAAGA-GASSER, Ana Maria ; FRANK, Natasha YCancer research (Chicago, Ill.), 2014-08, Vol.74 (15), p.4196-4207 [Periódico revisado por pares]Philadelphia, PA: American Association for Cancer ResearchTexto completo disponível |
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Material Type: Artigo
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Gain-of-Function Mutations in UPC2 Are a Frequent Cause of ERG11 Upregulation in Azole-Resistant Clinical Isolates of Candida albicansFlowers, Stephanie A ; Barker, Katherine S ; Berkow, Elizabeth L ; Toner, Geoffrey ; Chadwick, Sean G ; Gygax, Scott E ; Morschhäuser, Joachim ; Rogers, P DavidEukaryotic Cell, 2012-10, Vol.11 (10), p.1289-1299United States: American Society for MicrobiologyTexto completo disponível |
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Material Type: Artigo
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Spatiotemporally controlled single cell sonoporationFan, Zhenzhen ; Liu, Haiyan ; Mayer, Michael ; Deng, Cheri XProceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (41), p.16486-16491 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |