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1 |
Material Type: Artigo
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BCS class IV drugs: Highly notorious candidates for formulation developmentGhadi, Rohan ; Dand, NehaJournal of controlled release, 2017-02, Vol.248, p.71-95 [Periódico revisado por pares]Netherlands: Elsevier B.VTexto completo disponível |
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Material Type: Artigo
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Modulation of P-glycoprotein efflux pump: induction and activation as a therapeutic strategySilva, Renata ; Vilas-Boas, Vânia ; Carmo, Helena ; Dinis-Oliveira, Ricardo Jorge ; Carvalho, Félix ; de Lourdes Bastos, Maria ; Remião, FernandoPharmacology & therapeutics (Oxford), 2015-05, Vol.149, p.1-123 [Periódico revisado por pares]EnglandTexto completo disponível |
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Material Type: Artigo
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Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug BindingAller, Stephen G ; Yu, Jodie ; Ward, Andrew ; Weng, Yue ; Chittaboina, Srinivas ; Zhuo, Rupeng ; Harrell, Patina M ; Trinh, Yenphuong T ; Zhang, Qinghai ; Urbatsch, Ina L ; Chang, GeoffreyScience (American Association for the Advancement of Science), 2009-03, Vol.323 (5922), p.1718-1722 [Periódico revisado por pares]Washington, DC: American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Clinical Pharmacokinetics and Pharmacodynamics of AfatinibWind, Sven ; Schnell, David ; Ebner, Thomas ; Freiwald, Matthias ; Stopfer, PeterClinical pharmacokinetics, 2017-03, Vol.56 (3), p.235-250 [Periódico revisado por pares]Cham: Springer International PublishingTexto completo disponível |
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Material Type: Artigo
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A pH-Responsive Carrier System that Generates NO Bubbles to Trigger Drug Release and Reverse P-Glycoprotein-Mediated Multidrug ResistanceChung, Ming-Fan ; Liu, Hung-Yi ; Lin, Kun-Ju ; Chia, Wei-Tso ; Sung, Hsing-WenAngewandte Chemie (International ed.), 2015-08, Vol.54 (34), p.9890-9893 [Periódico revisado por pares]Weinheim: WILEY-VCH VerlagTexto completo disponível |
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Material Type: Artigo
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In vitro and in vivo P-glycoprotein transport characteristics of rivaroxabanGnoth, Mark Jean ; Buetehorn, Ulf ; Muenster, Uwe ; Schwarz, Thomas ; Sandmann, SteffenThe Journal of pharmacology and experimental therapeutics, 2011-07, Vol.338 (1), p.372-380 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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P-glycoprotein Inhibition as a Therapeutic Approach for Overcoming Multidrug Resistance in Cancer: Current Status and Future PerspectivesBinkhathlan, Ziyad ; Lavasanifar, AfsanehCurrent cancer drug targets, 2013-03, Vol.13 (3), p.326-346 [Periódico revisado por pares]Bentham Science Publishers LtdTexto completo disponível |
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Material Type: Artigo
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A "Silent" Polymorphism in the MDR1 Gene Changes Substrate SpecificityKimchi-Sarfaty, Chava ; Oh, Jung Mi ; Kim, In-Wha ; Sauna, Zuben E. ; Calcagno, Anna Maria ; Ambudkar, Suresh V. ; Gottesman, Michael M.Science (American Association for the Advancement of Science), 2007-01, Vol.315 (5811), p.525-528 [Periódico revisado por pares]Washington, DC: American Association for the Advancement of ScienceTexto completo disponível |
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Material Type: Artigo
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Amphiphilic carboxymethyl chitosan-quercetin conjugate with P-gp inhibitory properties for oral delivery of paclitaxelWang, Xiaoying ; Chen, Yihang ; Dahmani, Fatima Zohra ; Yin, Lifang ; Zhou, Jianping ; Yao, JingBiomaterials, 2014-08, Vol.35 (26), p.7654-7665 [Periódico revisado por pares]Netherlands: Elsevier LtdTexto completo disponível |
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Material Type: Artigo
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Nanomedicine for targeted cancer therapy: Towards the overcoming of drug resistanceShapira, Alina ; Livney, Yoav D ; Broxterman, Henk J ; Assaraf, Yehuda GDrug resistance updates, 2011-06, Vol.14 (3), p.150-163 [Periódico revisado por pares]Scotland: Elsevier LtdTexto completo disponível |