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1
Engineering of a recombinant NAGLU fusion protein with insulin-like growth factor 2 leads to improved cellular uptake via a glycosylation-independent lysosomal targeting pathway
Engineering of a recombinant NAGLU fusion protein with insulin-like growth factor 2 leads to improved cellular uptake via a glycosylation-independent lysosomal targeting pathway
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Engineering of a recombinant NAGLU fusion protein with insulin-like growth factor 2 leads to improved cellular uptake via a glycosylation-independent lysosomal targeting pathway

Aoyagi-Scharber, Mika ; Christianson, Terri ; Wendt, Daniel J. ; Tiger, Pascale M.N. ; Yip, Bryan K. ; Holtzinger, John ; Chen, Zhi ; Woloszynek, Josh ; Cheung, Diana S. ; Lo, Melanie J. ; Dickson, Patricia ; Fitzpatrick, Paul A. ; LeBowitz, Jonathan H.

Molecular genetics and metabolism, 2014-02, Vol.111 (2), p.S20-S20 [Periódico revisado por pares]

Elsevier Inc

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2
Clearance of Heparan Sulfate and Attenuation of CNS Pathology by Intracerebroventricular BMN 250 in Sanfilippo Type B Mice
Clearance of Heparan Sulfate and Attenuation of CNS Pathology by Intracerebroventricular BMN 250 in Sanfilippo Type B Mice
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Clearance of Heparan Sulfate and Attenuation of CNS Pathology by Intracerebroventricular BMN 250 in Sanfilippo Type B Mice

Aoyagi-Scharber, Mika ; Crippen-Harmon, Danielle ; Lawrence, Roger ; Vincelette, Jon ; Yogalingam, Gouri ; Prill, Heather ; Yip, Bryan K ; Baridon, Brian ; Vitelli, Catherine ; Lee, Amanda ; Gorostiza, Olivia ; Adintori, Evan G ; Minto, Wesley C ; Van Vleet, Jeremy L ; Yates, Bridget ; Rigney, Sara ; Christianson, Terri M ; Tiger, Pascale M N ; Lo, Melanie J ; Holtzinger, John ; Fitzpatrick, Paul A ; LeBowitz, Jonathan H ; Bullens, Sherry ; Crawford, Brett E ; Bunting, Stuart

Molecular therapy. Methods & clinical development, 2017-09, Vol.6 (C), p.43-53 [Periódico revisado por pares]

United States: Elsevier Limited

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3
Time- and dose-dependent normalization of pathological lysosomal storage and biochemistry in the mucopolysaccharidosis ΙΙΙΒ (MPS ΙΙΙΒ, Sanfilippo syndrome type Β) mouse model by intracerebroventricular enzyme replacement therapy with ΒΜΝ 250, a ΝAGLU-ΙGF2 fusion pro
Time- and dose-dependent normalization of pathological lysosomal storage and biochemistry in the mucopolysaccharidosis ΙΙΙΒ (MPS ΙΙΙΒ, Sanfilippo syndrome type Β) mouse model by intracerebroventricular enzyme replacement therapy with ΒΜΝ 250, a ΝAGLU-ΙGF2 fusion pro
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Time- and dose-dependent normalization of pathological lysosomal storage and biochemistry in the mucopolysaccharidosis ΙΙΙΒ (MPS ΙΙΙΒ, Sanfilippo syndrome type Β) mouse model by intracerebroventricular enzyme replacement therapy with ΒΜΝ 250, a ΝAGLU-ΙGF2 fusion pro

Aoyagi-Scharber, Mika ; Vincelette, Jon ; Lawrence, Roger ; Crippen-Harmon, Danielle ; Yip, Bryan K. ; Baridon, Brian ; Prill, Heather ; Minto, Wesley C. ; Van Vleet, Jeremy L. ; Vitelli, Catherine ; Adintori, Evan G. ; Christianson, Terri ; Tiger, Pascale M.N. ; Lo, Melanie J. ; Holtzinger, John ; Chen, Eric ; Webster, Katherine A. ; Brown, Jillian R. ; Fitzpatrick, Paul A. ; LeBowitz, Jonathan H. ; Bagri, Anil ; Bullens, Sherry ; Crawford, Brett E. ; Bunting, Stuart

Molecular genetics and metabolism, 2016-02, Vol.117 (2), p.S21-S21 [Periódico revisado por pares]

Elsevier Inc

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4
Histologic characterization of the progression of central nervous system pathology in the mucopolysaccharidosis IIIB (MPS IIIB, Sanfilippo syndrome type B) mouse model and bio-distribution and efficacy of the intracerebroventricular enzyme replacement therapy, BMN 250
Histologic characterization of the progression of central nervous system pathology in the mucopolysaccharidosis IIIB (MPS IIIB, Sanfilippo syndrome type B) mouse model and bio-distribution and efficacy of the intracerebroventricular enzyme replacement therapy, BMN 250
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Histologic characterization of the progression of central nervous system pathology in the mucopolysaccharidosis IIIB (MPS IIIB, Sanfilippo syndrome type B) mouse model and bio-distribution and efficacy of the intracerebroventricular enzyme replacement therapy, BMN 250

Bagri, Anil ; Harmon, Danielle ; Vincelette, Jon ; Vitelli, Catherine ; Minto, Wesley ; Yates, Bridget ; Rigney, Sara ; Santiago, Pam ; Baridon, Brian ; Xie, Lin ; Gorostiza, Olivia ; Christianson, Terri ; Tiger, Pascale M.N. ; Yip, Bryan K. ; Lo, Melanie J. ; Holtzinger, John ; Chen, Eric ; Aoyagi-Scharber, Mika ; Fitzpatrick, Paul ; LeBowitz, Jonathan H. ; Bullens, Sherry ; Bunting, Stuart

Molecular genetics and metabolism, 2016-02, Vol.117 (2), p.S23-S24 [Periódico revisado por pares]

Elsevier Inc

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5
Translational studies of intravenous and intracerebroventricular routes of administration for CNS cellular biodistribution for BMN 250, an enzyme replacement therapy for the treatment of Sanfilippo type B
Translational studies of intravenous and intracerebroventricular routes of administration for CNS cellular biodistribution for BMN 250, an enzyme replacement therapy for the treatment of Sanfilippo type B
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Translational studies of intravenous and intracerebroventricular routes of administration for CNS cellular biodistribution for BMN 250, an enzyme replacement therapy for the treatment of Sanfilippo type B

Grover, Anita ; Crippen-Harmon, Danielle ; Nave, Lacey ; Vincelette, Jon ; Wait, Jill C. M. ; Melton, Andrew C. ; Lawrence, Roger ; Brown, Jillian R. ; Webster, Katherine A. ; Yip, Bryan K. ; Baridon, Brian ; Vitelli, Catherine ; Rigney, Sara ; Christianson, Terri M. ; Tiger, Pascale M. N. ; Lo, Melanie J. ; Holtzinger, John ; Shaywitz, Adam J. ; Crawford, Brett E. ; Fitzpatrick, Paul A. ; LeBowitz, Jonathan H. ; Bullens, Sherry ; Aoyagi-Scharber, Mika ; Bunting, Stuart ; O’Neill, Charles A. ; Pinkstaff, Jason ; Bagri, Anil

Drug delivery and translational research, 2020-04, Vol.10 (2), p.425-439 [Periódico revisado por pares]

New York: Springer US

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6
The operation of a multiple stockroom
The operation of a multiple stockroom
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The operation of a multiple stockroom

Holtzinger, Albert H

Journal of chemical education, 1953-10, Vol.30 (10), p.512 [Periódico revisado por pares]

Division of Chemical Education

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7
Delivery of an enzyme-IGFII fusion protein to the mouse brain is therapeutic for mucopolysaccharidosis type IIIB
Delivery of an enzyme-IGFII fusion protein to the mouse brain is therapeutic for mucopolysaccharidosis type IIIB
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Delivery of an enzyme-IGFII fusion protein to the mouse brain is therapeutic for mucopolysaccharidosis type IIIB

Kan, Shih-hsin ; Aoyagi-Scharber, Mika ; Le, Steven Q. ; Vincelette, Jon ; Ohmi, Kazuhiro ; Bullens, Sherry ; Wendt, Daniel J. ; Christiansen, Terri M. ; Tiger, Pascale M. N. ; Brown, Julian R. ; Lawrence, Roger ; Yip, Bryan K. ; Holtzinger, John ; Bagri, Anil ; Crippen-Harmon, Danielle ; Vondrak, Kristen N. ; Chen, Zhi ; Hague, Chuck M. ; Woloszynek, Josh C. ; Cheung, Diana S. ; Webster, Katherine A. ; Adintori, Evan G. ; Lo, Melanie J. ; Wong, Wesley ; Fitzpatrick, Paul A. ; LeBowitz, Jonathan H. ; Crawford, Brett E. ; Bunting, Stuart ; Dickson, Patricia I. ; Neufeld, Elizabeth F.

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (41), p.14870-14875 [Periódico revisado por pares]

United States: National Academy of Sciences

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8
Differential Uptake of NAGLU-IGF2 and Unmodified NAGLU in Cellular Models of Sanfilippo Syndrome Type B
Differential Uptake of NAGLU-IGF2 and Unmodified NAGLU in Cellular Models of Sanfilippo Syndrome Type B
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Differential Uptake of NAGLU-IGF2 and Unmodified NAGLU in Cellular Models of Sanfilippo Syndrome Type B

Prill, Heather ; Luu, Amanda ; Yip, Bryan ; Holtzinger, John ; Lo, Melanie J. ; Christianson, Terri M. ; Yogalingam, Gouri ; Aoyagi-Scharber, Mika ; LeBowitz, Jonathan H. ; Crawford, Brett E. ; Lawrence, Roger

Molecular therapy. Methods & clinical development, 2019-09, Vol.14, p.56-63 [Periódico revisado por pares]

United States: Elsevier Inc

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9
WEB NECROSIS IN MUTE SWANS—A REPORT OF AN OUTBREAK
WEB NECROSIS IN MUTE SWANS—A REPORT OF AN OUTBREAK
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WEB NECROSIS IN MUTE SWANS—A REPORT OF AN OUTBREAK

YATES, VANCE J. ; MILLER, LOUISE T. ; JASTY, V. ; WILLEY, CHARLES H. ; HOLTZINGER, MARIAN

Bulletin of the Wildlife Disease Association, 1969-01, Vol.5 (1), p.33-34

Wildlife Disease Association

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10
BMN 250, a fusion of lysosomal alpha-N-acetylglucosaminidase with IGF2, exhibits different patterns of cellular uptake into critical cell types of Sanfilippo syndrome B disease pathogenesis
BMN 250, a fusion of lysosomal alpha-N-acetylglucosaminidase with IGF2, exhibits different patterns of cellular uptake into critical cell types of Sanfilippo syndrome B disease pathogenesis
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BMN 250, a fusion of lysosomal alpha-N-acetylglucosaminidase with IGF2, exhibits different patterns of cellular uptake into critical cell types of Sanfilippo syndrome B disease pathogenesis

Yogalingam, Gouri ; Luu, Amanda R ; Prill, Heather ; Lo, Melanie J ; Yip, Bryan ; Holtzinger, John ; Christianson, Terri ; Aoyagi-Scharber, Mika ; Lawrence, Roger ; Crawford, Brett E ; LeBowitz, Jonathan H Dardis, Andrea

PloS one, 2019-01, Vol.14 (1), p.e0207836-e0207836 [Periódico revisado por pares]

United States: Public Library of Science

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