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Enhancing chimeric antigen receptor T cell therapy by modulating the p53 signaling network with Δ133p53α
Enhancing chimeric antigen receptor T cell therapy by modulating the p53 signaling network with Δ133p53α
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Enhancing chimeric antigen receptor T cell therapy by modulating the p53 signaling network with Δ133p53α

Roselle, Christopher ; Horikawa, Izumi ; Chen, Linhui ; Kelly, Andre R ; Gonzales, Donna ; Da, Tong ; Wellhausen, Nils ; Rommel, Philipp C ; Baker, Daniel ; Suhoski, Megan ; Scholler, John ; O'Connor, Roddy S ; Young, Regina M ; Harris, Curtis C ; June, Carl H

Proceedings of the National Academy of Sciences - PNAS, 2024-03, Vol.121 (10), p.e2317735121-e2317735121 [Periódico revisado por pares]

United States: National Academy of Sciences

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2
Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera
Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera
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Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera

Tong, Yuquan ; Zhang, Peiyuan ; Yang, Xueyi ; Liu, Xiaohui ; Zhang, Jie ; Grudniewska, Magda ; Jung, Ikrak ; Abegg, Daniel ; Liu, Jun ; Childs-Disney, Jessica L ; Gibaut, Quentin M R ; Haniff, Hafeez S ; Adibekian, Alexander ; Mouradian, M Maral ; Disney, Matthew D

Proceedings of the National Academy of Sciences - PNAS, 2024-01, Vol.121 (2), p.e2306682120-e2306682120 [Periódico revisado por pares]

United States: National Academy of Sciences

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3
Effort Foraging Task reveals positive correlation between individual differences in the cost of cognitive and physical effort in humans
Effort Foraging Task reveals positive correlation between individual differences in the cost of cognitive and physical effort in humans
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Effort Foraging Task reveals positive correlation between individual differences in the cost of cognitive and physical effort in humans

Bustamante, Laura A ; Oshinowo, Temitope ; Lee, Jeremy R ; Tong, Elizabeth ; Burton, Allison R ; Shenhav, Amitai ; Cohen, Jonathan D ; Daw, Nathaniel D

Proceedings of the National Academy of Sciences - PNAS, 2023-12, Vol.120 (50), p.e2221510120 [Periódico revisado por pares]

United States: National Academy of Sciences

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4
Probing differences among Aβ oligomers with two triangular trimers derived from Aβ
Probing differences among Aβ oligomers with two triangular trimers derived from Aβ
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Probing differences among Aβ oligomers with two triangular trimers derived from Aβ

Kreutzer, Adam G ; Guaglianone, Gretchen ; Yoo, Stan ; Parrocha, Chelsea Marie T ; Ruttenberg, Sarah M ; Malonis, Ryan J ; Tong, Karen ; Lin, Yu-Fu ; Nguyen, Jennifer T ; Howitz, William J ; Diab, Michelle N ; Hamza, Imane L ; Lai, Jonathan R ; Wysocki, Vicki H ; Nowick, James S

Proceedings of the National Academy of Sciences - PNAS, 2023-05, Vol.120 (22), p.e2219216120 [Periódico revisado por pares]

United States: National Academy of Sciences

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5
Breast cancer patient-derived whole-tumor cell culture model for efficient drug profiling and treatment response prediction
Breast cancer patient-derived whole-tumor cell culture model for efficient drug profiling and treatment response prediction
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Breast cancer patient-derived whole-tumor cell culture model for efficient drug profiling and treatment response prediction

Chen, Xinsong ; Sifakis, Emmanouil G ; Robertson, Stephanie ; Neo, Shi Yong ; Jun, Seong-Hwan ; Tong, Le ; Hui Min, Apple Tay ; Lövrot, John ; Hellgren, Roxanna ; Margolin, Sara ; Bergh, Jonas ; Foukakis, Theodoros ; Lagergren, Jens ; Lundqvist, Andreas ; Ma, Ran ; Hartman, Johan

Proceedings of the National Academy of Sciences - PNAS, 2023-01, Vol.120 (1), p.e2209856120-e2209856120 [Periódico revisado por pares]

United States: National Academy of Sciences

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6
A blood-brain penetrant RNA-targeted small molecule triggers elimination of r(G 4 C 2 ) exp in c9ALS/FTD via the nuclear RNA exosome
A blood-brain penetrant RNA-targeted small molecule triggers elimination of r(G 4 C 2 ) exp in c9ALS/FTD via the nuclear RNA exosome
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A blood-brain penetrant RNA-targeted small molecule triggers elimination of r(G 4 C 2 ) exp in c9ALS/FTD via the nuclear RNA exosome

Bush, Jessica A ; Meyer, Samantha M ; Fuerst, Rita ; Tong, Yuquan ; Li, Yue ; Benhamou, Raphael I ; Aikawa, Haruo ; Zanon, Patrick R A ; Gibaut, Quentin M R ; Angelbello, Alicia J ; Gendron, Tania F ; Zhang, Yong-Jie ; Petrucelli, Leonard ; Heick Jensen, Torben ; Childs-Disney, Jessica L ; Disney, Matthew D

Proceedings of the National Academy of Sciences - PNAS, 2022-11, Vol.119 (48), p.e2210532119 [Periódico revisado por pares]

United States: National Academy of Sciences

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7
Friction-driven membrane scission by the human ESCRT-III proteins CHMP1B and IST1
Friction-driven membrane scission by the human ESCRT-III proteins CHMP1B and IST1
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Friction-driven membrane scission by the human ESCRT-III proteins CHMP1B and IST1

Cada, A King ; Pavlin, Mark R ; Castillo, Juan P ; Tong, Alexander B ; Larsen, Kevin P ; Ren, Xuefeng ; Yokom, Adam L ; Tsai, Feng-Ching ; Shiah, Jamie V ; Bassereau, Patricia M ; Bustamante, Carlos J ; Hurley, James H

Proceedings of the National Academy of Sciences - PNAS, 2022-07, Vol.119 (29), p.e2204536119-e2204536119 [Periódico revisado por pares]

United States: National Academy of Sciences

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8
Genetic architecture facilitates then constrains adaptation in a host-parasite coevolutionary arms race
Genetic architecture facilitates then constrains adaptation in a host-parasite coevolutionary arms race
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Genetic architecture facilitates then constrains adaptation in a host-parasite coevolutionary arms race

Spottiswoode, Claire N ; Tong, Wenfei ; Jamie, Gabriel A ; Stryjewski, Katherine F ; DaCosta, Jeffrey M ; Kuras, Evan R ; Green, Ailsa ; Hamama, Silky ; Taylor, Ian G ; Moya, Collins ; Sorenson, Michael D

Proceedings of the National Academy of Sciences - PNAS, 2022-04, Vol.119 (17), p.e2121752119-e2121752119 [Periódico revisado por pares]

United States: National Academy of Sciences

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9
Destabilization of β Cell FIT2 by saturated fatty acids alter lipid droplet numbers and contribute to ER stress and diabetes
Destabilization of β Cell FIT2 by saturated fatty acids alter lipid droplet numbers and contribute to ER stress and diabetes
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Destabilization of β Cell FIT2 by saturated fatty acids alter lipid droplet numbers and contribute to ER stress and diabetes

Zheng, Xiaofeng ; Ho, Qing Wei Calvin ; Chua, Minni ; Stelmashenko, Olga ; Yeo, Xin Yi ; Muralidharan, Sneha ; Torta, Federico ; Chew, Elaine Guo Yan ; Lian, Michelle Mulan ; Foo, Jia Nee ; Jung, Sangyong ; Wong, Sunny Hei ; Tan, Nguan Soon ; Tong, Nanwei ; Rutter, Guy A ; Wenk, Markus R ; Silver, David L ; Berggren, Per-Olof ; Ali, Yusuf

Proceedings of the National Academy of Sciences - PNAS, 2022-03, Vol.119 (11), p.e2113074119-e2113074119 [Periódico revisado por pares]

United States: National Academy of Sciences

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10
Decoding the information structure underlying the neural representation of concepts
Decoding the information structure underlying the neural representation of concepts
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Decoding the information structure underlying the neural representation of concepts

Fernandino, Leonardo ; Tong, Jia-Qing ; Conant, Lisa L ; Humphries, Colin J ; Binder, Jeffrey R

Proceedings of the National Academy of Sciences - PNAS, 2022-02, Vol.119 (6), p.1 [Periódico revisado por pares]

United States: National Academy of Sciences

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