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Discovery of 3,3-dimethyl-5-hydroxypipecolic hydroxamate-based inhibitors of aggrecanase and MMP-13
Discovery of 3,3-dimethyl-5-hydroxypipecolic hydroxamate-based inhibitors of aggrecanase and MMP-13
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Discovery of 3,3-dimethyl-5-hydroxypipecolic hydroxamate-based inhibitors of aggrecanase and MMP-13

Noe, Mark C. ; Natarajan, Vijayalakshmi ; Snow, Sheri L. ; Mitchell, Peter G. ; Lopresti-Morrow, Lori ; Reeves, Lisa M. ; Yocum, Sue A. ; Carty, Thomas J. ; Barberia, John A. ; Sweeney, Francis J. ; Liras, Jennifer L. ; Vaughn, Marcie ; Hardink, Joel R. ; Hawkins, Joel M. ; Tokar, Christopher

Bioorganic & medicinal chemistry letters, 2005-06, Vol.15 (11), p.2808-2811 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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2
Synthesis and biological activity of selective pipecolic acid-based TNF-α converting enzyme (TACE) inhibitors
Synthesis and biological activity of selective pipecolic acid-based TNF-α converting enzyme (TACE) inhibitors
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Synthesis and biological activity of selective pipecolic acid-based TNF-α converting enzyme (TACE) inhibitors

Letavic, Michael A. ; Axt, Matt Z. ; Barberia, John T. ; Carty, Thomas J. ; Danley, Dennis E. ; Geoghegan, Kieran F. ; Halim, Nadia S. ; Hoth, Lise R. ; Kamath, Ajith V. ; Laird, Ellen R. ; Lopresti-Morrow, Lori L. ; McClure, Kim F. ; Mitchell, Peter G. ; Natarajan, Vijayalakshmi ; Noe, Mark C. ; Pandit, Jayvardhan ; Reeves, Lisa ; Schulte, Gayle K. ; Snow, Sheri L. ; Sweeney, Francis J. ; Tan, Douglas H. ; Yu, Chul H.

Bioorganic & medicinal chemistry letters, 2002-05, Vol.12 (10), p.1387-1390 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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3
Discovery of 3-OH-3-methylpipecolic hydroxamates: Potent orally active inhibitors of aggrecanase and MMP-13
Discovery of 3-OH-3-methylpipecolic hydroxamates: Potent orally active inhibitors of aggrecanase and MMP-13
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Discovery of 3-OH-3-methylpipecolic hydroxamates: Potent orally active inhibitors of aggrecanase and MMP-13

Noe, Mark C. ; Natarajan, Vijayalakshmi ; Snow, Sheri L. ; Wolf-Gouveia, Lilli A. ; Mitchell, Peter G. ; Lopresti-Morrow, Lori ; Reeves, Lisa M. ; Yocum, Sue A. ; Otterness, Ivan ; Bliven, Marcia A. ; Carty, Thomas J. ; Barberia, John T. ; Sweeney, Francis J. ; Liras, Jennifer L. ; Vaughn, Marcie

Bioorganic & medicinal chemistry letters, 2005-07, Vol.15 (14), p.3385-3388 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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4
Synthesis and biological activity of piperazine-Based dual MMP-13 and TNF-α converting enzyme inhibitors
Synthesis and biological activity of piperazine-Based dual MMP-13 and TNF-α converting enzyme inhibitors
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Synthesis and biological activity of piperazine-Based dual MMP-13 and TNF-α converting enzyme inhibitors

Letavic, Michael A. ; Barberia, John T. ; Carty, Thomas J. ; Hardink, Joel R. ; Liras, Jennifer ; Lopresti-Morrow, Lori L. ; Mitchell, Peter G. ; Noe, Mark C. ; Reeves, Lisa M. ; Snow, Sheri L. ; Stam, Ethan J. ; Sweeney, Francis J. ; Vaughn, Marcie L. ; Yu, Chul H.

Bioorganic & medicinal chemistry letters, 2003-10, Vol.13 (19), p.3243-3246 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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5
Benzimidazolone p38 inhibitors
Benzimidazolone p38 inhibitors
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Benzimidazolone p38 inhibitors

DOMBROSKI, Mark A ; LETAVIC, Michael A ; JORDAN, Crystal K ; LABASI, Jeff M ; MARTIN, William H ; PEESE, Kevin M ; STOCK, Ingrid A ; SVENSSON, Linne ; SWEENEY, Francis J ; YU, Chul H ; MCCLURE, Kim F ; BARBERIA, John T ; CARTY, Thomas J ; CORTINA, Santo R ; CSIKI, Csilla ; DIPESA, Alan J ; ELLIOTT, Nancy C ; GABEL, Christopher A

Bioorganic & medicinal chemistry letters, 2004-02, Vol.14 (4), p.919-923 [Periódico revisado por pares]

Oxford: Elsevier

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6
Structure–activity relationships of triazolopyridine oxazole p38 inhibitors: Identification of candidates for clinical development
Structure–activity relationships of triazolopyridine oxazole p38 inhibitors: Identification of candidates for clinical development
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Structure–activity relationships of triazolopyridine oxazole p38 inhibitors: Identification of candidates for clinical development

McClure, Kim F. ; Letavic, Michael A. ; Kalgutkar, Amit S. ; Gabel, Christopher A. ; Audoly, Laurent ; Barberia, John T. ; Braganza, John F. ; Carter, Demetrius ; Carty, Thomas J. ; Cortina, Santo R. ; Dombroski, Mark A. ; Donahue, Kathleen M. ; Elliott, Nancy C. ; Gibbons, Colleen P. ; Jordan, Crystal K. ; Kuperman, Alexander V. ; Labasi, Jeff M. ; LaLiberte, Ronald E. ; McCoy, Jennifer M. ; Naiman, Brian M. ; Nelson, Kendra L. ; Nguyen, Hang T. ; Peese, Kevin M. ; Sweeney, Francis J. ; Taylor, Timothy J. ; Trebino, Catherine E. ; Abramov, Yuriy A. ; Laird, Ellen R. ; Volberg, Walter A. ; Zhou, Jun ; Bach, Justin ; Lombardo, Franco

Bioorganic & medicinal chemistry letters, 2006-08, Vol.16 (16), p.4339-4344 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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