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1 |
Material Type: Artigo
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1-[(1-Methyl-1H-imidazol-2-yl)methyl]-4-phenylpiperidines as mGluR2 Positive Allosteric Modulators for the Treatment of PsychosisZhang, Lei ; Brodney, Michael A ; Candler, John ; Doran, Angela C ; Duplantier, Allen J ; Efremov, Ivan V ; Evrard, Edel ; Kraus, Kenneth ; Ganong, Alan H ; Haas, Jessica A ; Hanks, Ashley N ; Jenza, Keith ; Lazzaro, John T ; Maklad, Noha ; McCarthy, Sheryl A ; Qian, Weimin ; Rogers, Bruce N ; Rottas, Melinda D ; Schmidt, Christopher J ; Siuciak, Judith A ; Tingley, F. David ; Zhang, Andy QJournal of medicinal chemistry, 2011-03, Vol.54 (6), p.1724-1739 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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(1-(4-(Naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine: A Wingless β-Catenin Agonist That Increases Bone Formation RatePelletier, Jeffrey C ; Lundquist, Joseph T ; Gilbert, Adam M ; Alon, Nipa ; Bex, Frederick J ; Bhat, Bheem M ; Bursavich, Mattew G ; Coleburn, Valerie E ; Felix, Luciana A ; Green, Daniel M ; Green, Paula ; Hauze, Diane B ; Kharode, Yogendra P ; Lam, Ho-Sun ; Lockhead, Susan R ; Magolda, Ronald L ; Matteo, Jeanne J ; Mehlmann, John F ; Milligan, Colleen ; Murrills, Richard J ; Pirrello, Jennifer ; Selim, Sally ; Sharp, Michael C ; Unwalla, Ray J ; Vera, Matthew D ; Wrobel, Jay E ; Yaworsky, Paul ; Bodine, Peter V. NJournal of medicinal chemistry, 2009-11, Vol.52 (22), p.6962-6965 [Periódico revisado por pares]United States: American Chemical SocietyTexto completo disponível |
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Material Type: Artigo
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[ 11 C]CHDI-626, a PET Tracer Candidate for Imaging Mutant Huntingtin Aggregates with Reduced Binding to AD Pathological ProteinsLiu, Longbin ; Johnson, Peter D ; Prime, Michael E ; Khetarpal, Vinod ; Lee, Matthew R ; Brown, Christopher J ; Chen, Xuemei ; Clark-Frew, Daniel ; Coe, Samuel ; Conlon, Mike ; Davis, Randall ; Ensor, Samantha ; Esposito, Simone ; Moren, Anton Forsberg ; Gai, Xinjie ; Green, Samantha ; Greenaway, Catherine ; Haber, James ; Halldin, Christer ; Hayes, Sarah ; Herbst, Todd ; Herrmann, Frank ; Heßmann, Manuela ; Hsai, Ming Min ; Kotey, Adrian ; Mangette, John E ; Mills, Matthew R ; Monteagudo, Edith ; Nag, Sangram ; Nibbio, Martina ; Orsatti, Laura ; Schaertl, Sabine ; Scheich, Christoph ; Sproston, Joanne ; Stepanov, Vladimir ; Varnäs, Katarina ; Varrone, Andrea ; Wityak, John ; Mrzljak, Ladislav ; Munoz-Sanjuan, Ignacio ; Bard, Jonathan A ; Dominguez, CeliaJournal of medicinal chemistry, 2021-08, Vol.64 (16), p.12003-12021 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Inhibitors Still Improve Metabolic Phenotype in Male 11β-HSD1 Knockout Mice Suggesting Off-Target MechanismsHarno, Erika ; Cottrell, Elizabeth C ; Yu, Alice ; DeSchoolmeester, Joanne ; Gutierrez, Pablo Morentin ; Denn, Mark ; Swales, John G ; Goldberg, Fred W ; Bohlooly-Y, Mohammad ; Andersén, Harriet ; Wild, Martin J ; Turnbull, Andrew V ; Leighton, Brendan ; White, AnneEndocrinology (Philadelphia), 2013-12, Vol.154 (12), p.4580-4593 [Periódico revisado por pares]Chevy Chase, MD: Endocrine SocietyTexto completo disponível |
5 |
Material Type: Artigo
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11β-Hydroxysteroid Dehydrogenase Type 2 Deficiency Accelerates Atherogenesis and Causes Proinflammatory Changes in the Endothelium in Apoe−/− MiceDeuchar, Graeme A ; McLean, Danielle ; Hadoke, Patrick W. F ; Brownstein, David G ; Webb, David J ; Mullins, John J ; Chapman, Karen ; Seckl, Jonathan R ; Kotelevtsev, Yuri VEndocrinology (Philadelphia), 2011-01, Vol.152 (1), p.236-246 [Periódico revisado por pares]United States: Endocrine SocietyTexto completo disponível |
6 |
Material Type: Artigo
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12(S)-Hydroxyeicosatetraenoic Acid and 13(S)-Hydroxyoctadecadienoic Acid Regulation of Protein Kinase C-α in Melanoma Cells: Role of Receptor-Mediated Hydrolysis of Inositol PhospholipidsLiu, Bin ; Khan, Wasiuddin A. ; Hannun, Yusuf A. ; Timar, Jozsef ; Taylor, John D. ; Lundy, Steven ; Butovich, Igor ; Honn, Kenneth V.Proceedings of the National Academy of Sciences - PNAS, 1995-09, Vol.92 (20), p.9323-9327 [Periódico revisado por pares]United States: National Academy of Sciences of the United States of AmericaTexto completo disponível |
7 |
Material Type: Artigo
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12(S)‐hydroxyeicosatetraenoic acid increases the actin microfilament content in B16a melanoma cells: A protein kinase‐dependent processRice, Renee L. ; Tang, Dean G. ; Haddad, Maher ; Honn, Kenneth V. ; Taylor, John D.International journal of cancer, 1998-07, Vol.77 (2), p.271-278 [Periódico revisado por pares]New York: Wiley Subscription Services, Inc., A Wiley CompanyTexto completo disponível |
8 |
Material Type: Artigo
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17α-Estradiol promotes ovarian aging in growth hormone receptor knockout mice, but not wild-type littermatesIsola, José V.V. ; Zanini, Bianka M. ; Sidhom, Silvana ; Kopchick, John J. ; Bartke, Andrzej ; Masternak, Michal M. ; Stout, Michael B. ; Schneider, AugustoExperimental gerontology, 2020-01, Vol.129, p.110769-110769, Article 110769 [Periódico revisado por pares]England: Elsevier IncTexto completo disponível |
9 |
Material Type: Artigo
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18F-labeled FECNT: a selective radioligand for PET imaging of brain dopamine transportersGoodman, Mark M ; Kilts, Clinton D ; Keil, Robert ; Shi, Bing ; Martarello, Laurent ; Xing, Dongxia ; Votaw, John ; Ely, Timothy D ; Lambert, Philip ; Owens, Michael J ; Camp, Vernon M ; Malveaux, Eugene ; Hoffman, John MNuclear medicine and biology, 2000, Vol.27 (1), p.1-12 [Periódico revisado por pares]Amsterdam: Elsevier IncTexto completo disponível |
10 |
Material Type: Report
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1966 RESEARCH CLERKSHIP REPORTSBlasko,John C ; Boysen,Philip G ; Graham,Hurlis V , Jr ; Holt,Don F ; Kaufman,Joseph A1967Texto completo disponível |