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Material Type: Artículo
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Targeting mTOR: prospects for mTOR complex 2 inhibitors in cancer therapySPARKS, C. A ; GUERTIN, D. AOncogene, 2010-07, Vol.29 (26), p.3733-3744 [Revista revisada por pares]Basingstoke: Nature Publishing GroupTexto completo disponible |
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Material Type: Artículo
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Non-canonical mTORC2 Signaling Regulates Brown Adipocyte Lipid Catabolism through SIRT6-FoxO1Jung, Su Myung ; Hung, Chien-Min ; Hildebrand, Samuel R. ; Sanchez-Gurmaches, Joan ; Martinez-Pastor, Barbara ; Gengatharan, Jivani M. ; Wallace, Martina ; Mukhopadhyay, Dimpi ; Martinez Calejman, Camila ; Luciano, Amelia K. ; Hsiao, Wen-Yu ; Tang, Yuefeng ; Li, Huawei ; Daniels, Danette L. ; Mostoslavsky, Raul ; Metallo, Christian M. ; Guertin, David A.Molecular cell, 2019-08, Vol.75 (4), p.807-822.e8 [Revista revisada por pares]United States: Elsevier IncTexto completo disponible |
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Material Type: Artículo
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Proteome and Phosphoproteome Analysis of Brown Adipocytes Reveals That RICTOR Loss Dampens Global Insulin/AKT SignalingEntwisle, Samuel W. ; Martinez Calejman, Camila ; Valente, Anthony S. ; Lawrence, Robert T. ; Hung, Chien-Min ; Guertin, David A. ; Villén, JuditMolecular & cellular proteomics, 2020-07, Vol.19 (7), p.1104-1119 [Revista revisada por pares]United States: Elsevier IncTexto completo disponible |
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Critical focus on mechanisms of resistance and toxicity of m-TOR inhibitors in pancreatic neuroendocrine tumorsAntonuzzo, L ; Del Re, M ; Barucca, V ; Spada, F ; Meoni, G ; Restante, G ; Danesi, R ; Di Costanzo, F ; Fazio, NCancer treatment reviews, 2017-06, Vol.57, p.28-35 [Revista revisada por pares]Netherlands: Elsevier LtdTexto completo disponible |
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Material Type: Artículo
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Developing Novel Experimental Models of m-TORopathic Epilepsy and Related Neuropathologies: Translational Insights from Zebrafishde Abreu, Murilo S ; Demin, Konstantin A ; Kotova, Maria M ; Mirzaei, Foad ; Shariff, Sanobar ; Kantawala, Burhan ; Zakharchenko, Ksenia V ; Kolesnikova, Tatiana O ; Dilbaryan, Karen ; Grigoryan, Artem ; Yenkoyan, Konstantin B ; Kalueff, Allan VInternational journal of molecular sciences, 2023-01, Vol.24 (2), p.1530 [Revista revisada por pares]Switzerland: MDPI AGTexto completo disponible |
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Material Type: Artículo
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Pathogenic Role of mTORC1 and mTORC2 in Pulmonary HypertensionTang, Haiyang, PhD ; Wu, Kang, MD, PhD ; Wang, Jian, MD ; Vinjamuri, Sujana, MD, MS ; Gu, Yali, MS, RN ; Song, Shanshan, MD, PhD ; Wang, Ziyi, MD ; Zhang, Qian, MD ; Balistrieri, Angela ; Ayon, Ramon J., PhD ; Rischard, Franz, MD ; Vanderpool, Rebecca, PhD ; Chen, Jiwang, PhD ; Zhou, Guofei, PhD ; Desai, Ankit A., MD ; Black, Stephen M., PhD ; Garcia, Joe G.N., MD ; Yuan, Jason X.-J., MD, PhD ; Makino, Ayako, PhDJACC. Basic to translational science, 2018-12, Vol.3 (6), p.744-762 [Revista revisada por pares]United States: Elsevier IncTexto completo disponible |
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Material Type: Artículo
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Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translationPRADELLI, L. A ; BENETEAU, M ; CHAUVIN, C ; JACQUIN, M. A ; MARCHETTI, S ; MUNOZ-PINEDO, C ; AUBERGER, P ; PENDE, M ; RICCI, J.-EOncogene, 2010-03, Vol.29 (11), p.1641-1652 [Revista revisada por pares]Basingstoke: Nature Publishing GroupTexto completo disponible |
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Material Type: Artículo
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mTOR phosphorylated at S2448 binds to raptor and rictorRosner, M ; Siegel, N ; Valli, A ; Fuchs, C ; Hengstschläger, MAmino acids, 2010-01, Vol.38 (1), p.223-228 [Revista revisada por pares]Vienna: Vienna : Springer ViennaTexto completo disponible |
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Material Type: Artículo
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Twenty-five years of mTOR: Uncovering the link from nutrients to growthSabatini, David M.Proceedings of the National Academy of Sciences - PNAS, 2017-11, Vol.114 (45), p.11818-11825 [Revista revisada por pares]United States: National Academy of SciencesTexto completo disponible |
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Material Type: Artículo
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Mammalian target of rapamycin (mTOR): a central regulator of male fertility?Jesus, Tito T. ; Oliveira, Pedro F. ; Sousa, Mário ; Cheng, C. Yan ; Alves, Marco G.Critical reviews in biochemistry and molecular biology, 2017-05, Vol.52 (3), p.235-253 [Revista revisada por pares]England: Taylor & FrancisTexto completo disponible |