Cell-free DNA fragmentation profiling for therapeutic response monitoring in metastatic colorectal cancer

Skidmore, Zachary L. ; van 't Erve, Iris ; Lumbard, Keith ; Alipanahi, Bahar ; Keefer, Laurel ; Rinaldi, Lorenzo ; Carey, Jacob ; Tom, Jennifer ; Punt, Cornelis J. A. ; Dracopoli, Nicholas C. ; Meijer, Gerrit A. ; Scharpf, Robert B. ; Velculescu, Victor E. ; Fijneman, Remond ; Leal, Alessandro

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Dissecting small cell lung cancer subtypes with cell-free DNA fragmentomes

Rinaldi, Lorenzo ; Skidmore, Zachary L. ; Alipanahi, Bahar ; Graham, Garrett ; Chesnick, Bryan ; Takahashi, Nobuyuki ; Kumar, Rajesh ; Goyal, Shubhank ; Abel, Melissa Lauren ; Malin, Justin ; Desai, Parth Anil ; Dracopoli, Nicholas C. ; Velculescu, Victor E. ; Thomas, Anish ; Leal, Alessandro

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Prospective evaluation of cell-free DNA fragmentation profiles for lung cancer detection

Wong, Kwok-Kin ; Mazzone, Peter J. ; Tsay, Jun-Chieh ; Pass, Harvey I. ; Vachani, Anil ; Thompson, Jeffrey C. ; Ryan, Allison ; Carey, Jacob ; Jakubowski, Debbie ; Wu, Tony ; Zong, Yuhua ; Portwood, Carter ; Lumbard, Keith ; Catallini, Joseph ; Arjungi, Kavita ; Birch, Ashley ; Leal, Alessandro ; Bach, Peter Brian ; Scharpf, Robert B. ; Velculescu, Victor E.

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Analysis of cell-free DNA (cfDNA) fragmentomes and prediction scores across distinct molecular subtypes

Schuurbiers, Milou ; Leal, Alessandro ; Aghamirzaie, Delasa ; Chesnick, Bryan ; Peters, Erica ; Wu, Tony ; Jakubowski, Debbie ; Tom, Jennifer ; Dracopoli, Nicholas C. ; Bach, Peter B. ; Scharpf, Robert B. ; Velculescu, Victor E. ; Monkhorst, Kim ; van den Broek, Daan ; van den Heuvel, Michel

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Impact of early-onset colorectal cancer on utilization of chemotherapy and outcomes in patients with stage II disease

Leary, Jacob Beck ; Hu, Junxiao ; Davis, Sean ; Leal, Alexis Diane ; Davis, S. Lindsey ; Kim, Sunnie S. ; Lentz, Robert William ; Friedrich, Tyler ; Vogel, Jon ; Herter, Whitney ; Chapman, Brandon C. ; Messersmith, Wells A. ; Lieu, Christopher Hanyoung

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First-in-Human Phase I/IB Dose-Finding Study of Adagrasib (MRTX849) in Patients With Advanced KRASG12C Solid Tumors (KRYSTAL-1)

Ou, Sai-Hong Ignatius ; Jänne, Pasi A. ; Leal, Ticiana A. ; Rybkin, Igor I. ; Sabari, Joshua K. ; Barve, Minal A. ; Bazhenova, Lyudmila ; Johnson, Melissa L. ; Velastegui, Karen L. ; Cilliers, Cornelius ; Christensen, James G. ; Yan, Xiaohong ; Chao, Richard C. ; Papadopoulos, Kyriakos P.

Wolters Kluwer Health

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First-in-Human Phase I/IB Dose-Finding Study of Adagrasib (MRTX849) in Patients With Advanced KRAS G12C Solid Tumors (KRYSTAL-1)

Ou, Sai-Hong Ignatius ; Jänne, Pasi A ; Leal, Ticiana A ; Rybkin, Igor I ; Sabari, Joshua K ; Barve, Minal A ; Bazhenova, Lyudmila ; Johnson, Melissa L ; Velastegui, Karen L ; Cilliers, Cornelius ; Christensen, James G ; Yan, Xiaohong ; Chao, Richard C ; Papadopoulos, Kyriakos P

United States

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First-in-Human Phase I/IB Dose-Finding Study of Adagrasib (MRTX849) in Patients With Advanced KRASG12C Solid Tumors (KRYSTAL-1)

Ou, Sai-Hong Ignatius ; Jänne, Pasi A ; Leal, Ticiana A ; Rybkin, Igor I ; Sabari, Joshua K ; Barve, Minal A ; Bazhenova, Lyudmila ; Johnson, Melissa L ; Velastegui, Karen L ; Cilliers, Cornelius ; Christensen, James G ; Yan, Xiaohong ; Chao, Richard C ; Papadopoulos, Kyriakos P

eScholarship, University of California

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Cell-free DNA (cfDNA) fragmentomes predict tumor burden in metastatic colorectal cancer (mCRC)

Leal, Alessandro ; van 't Erve, Iris ; Lumbard, Keith ; Keefer, Laurel ; Carey, Jacob ; Wu, Tony ; Jakubowski, Debbie ; Butler, Denise ; Rongione, Michael ; Chesnick, Bryan ; Punt, Cornelis J. A. ; Meijer, Gerrit A. ; Dracopoli, Nicholas C ; Maddala, Tara ; Scharpf, Robert ; Bach, Peter Brian ; Velculescu, Victor E. ; Fijneman, Remond

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LungTS: A new gene expression signature for prediction of response to checkpoint inhibitors in non-small cell lung cancer

De Marchi, Pedro ; Ferro Leal, Leticia ; da Silva, Luciane Sussuchi ; de Oliveira Cavagna, Rodrigo ; Ferreira da Silva, Flavio Augusto ; da Silva, Vinicius Duval ; da Silva, Eduardo CA ; Saito, Augusto Obuti ; Aguado, Cristina ; Bracht, Jill ; Gonzalez-Cao, Maria ; Giménez-Capitán, Ana ; Pedraz, Carlos ; Sá, Daniella Dias Silva ; Molina Vila, Miguel Angel ; Cordeiro De Lima, Vladmir Claudio ; Reis, Rui Manuel

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