Idioma:

Approaches to gene mapping in complex human diseases

Jonathan L Haines 1957-; Margaret Ann Pericak-Vance

Localização: IB - Instituto de Biociências (QH445.2 A652 )(Acessar)

Título:
Approaches to gene mapping in complex human diseases
Autor: Jonathan L Haines 1957-; Margaret Ann Pericak-Vance
Assuntos: Genetic disorders; Human gene mapping; MAPEAMENTO GENÉTICO; DOENÇAS HEREDITÁRIAS; GENÓTIPOS; MAPEAMENTO CROMOSSÔMICO; Genetic Diseases, Inborn -- genetics; Chromosome Mapping; Genetic Markers; Genotype
Notas: Includes bibliographical references and index
Descrição: Overview of mapping common and genetically complex human disease traits -- Basic concepts in genetics -- Defining disease phenotypes -- Basic concepts in linkage analysis -- Determining the genetic component of a disease -- Pat ient and family participation in genetic research studies -- Sample size and power -- The collection of biological samples for DNA analysis -- Methods of genotyping Database design for gene mapping studies -- Genomic screening -- Lod score analysis -- Sib pair analysis -- Affected relative pair analysis -- Linkage disequilibrium and allelic association -- Using public databases -- Laborato ry approaches toward gene identification -- Examining complex genetic interactions -- Glossary -- Appendix: useful websites for genetic analysis
Editor: New York Wiley-Liss
Data de criação/publicação: c1998
Formato: xxii, 434 p. ill. 25 cm.
Idioma: Inglês

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