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The effects of preoperative oral antibiotic use on the development of surgical site infection after elective colorectal resections: a retrospective cohort analysis in consecutively operated 90 patients

Ozdemir, Suleyman, M.D ; Gulpinar, Kamil, M.D ; Ozis, S. Erpulat, M.D ; Sahli, Zafer, M.D ; Korkmaz, Atila, M.D ; Gecim, I. Ethem, M.D

International journal of surgery (London, England), 2016-09, Vol.33, p.102-108 [Periódico revisado por pares]

England: Elsevier Ltd

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Título:
The effects of preoperative oral antibiotic use on the development of surgical site infection after elective colorectal resections: a retrospective cohort analysis in consecutively operated 90 patients
Autor: Ozdemir, Suleyman, M.D ; Gulpinar, Kamil, M.D ; Ozis, S. Erpulat, M.D ; Sahli, Zafer, M.D ; Korkmaz, Atila, M.D ; Gecim, I. Ethem, M.D
Assuntos: Administration, Oral ; Adult ; Aged ; Aged, 80 and over ; Anastomotic Leak - epidemiology ; Anti-Bacterial Agents - administration & dosage ; Antibiotic Prophylaxis ; Colectomy - adverse effects ; Colitis, Ulcerative - surgery ; Colonic Neoplasms - surgery ; Colorectal resection ; Elective Surgical Procedures - adverse effects ; Female ; Hospital Costs ; Humans ; Length of Stay ; Male ; Metronidazole - administration & dosage ; Middle Aged ; Oral antibiotic prophylaxis ; Preoperative Care ; Retrospective Studies ; Surgery ; Surgical site infection ; Surgical Wound Infection - epidemiology ; Surgical Wound Infection - prevention & control ; Young Adult
É parte de: International journal of surgery (London, England), 2016-09, Vol.33, p.102-108
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
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Descrição: Abstract Purpose The influence of oral antibiotic use together with mechanical bowel preparation (MBP) on surgical site infection (SSI) rate, length of hospital stay and total hospital costs in patients undergoing elective colorectal surgery were evaluated in this study. Methods Data from 90 consecutive patients undergoing elective colorectal resection between October 2006 and September 2009 was analyzed retrospectively. All patients received MBP. Patients in group A were given oral antibiotics (a total 480 mg of gentamycin, 4 gr of metronidazole in two divided doses and 2 mg of bisacodyl PO), whereas patients in group B received no oral antibiotics. Exclusion criteria were emergent operations, laparoscopic operations, preoperative chemoradiotherapy, intraoperative colonoscopy prior to the creation of an anastomosis or antibiotic use within the previous 10 days. SSI, length of hospital stays and total hospital charges were evaluated. Results Patients in both study groups, group A (n=45) and group B (n=45), were similar in terms of age, BMI, diverting ileostomy creation, localization and stage of the disease. Patients receiving oral antibiotics demonstrated a lower rate of wound infections (36% vs. 71%, p<0.001), shorter hospital stay (8.1±2.4 days vs. 14.2±10.9 days, respectively, p<0.001) and similar rates for anastomotic leakage (2% vs. 11%, p=0.20). The mean ± SD total hospital charges were significantly lower in Group A (2.699±0.892 $) than that in Group B (4.411±4.995$, p=0.029). Conclusion Preoperative oral antibiotic use with MBP may provide faster recovery with less SSI and hospital charges.
Editor: England: Elsevier Ltd
Idioma: Inglês

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The effects of preoperative oral antibiotic use on the development of surgical site infection after elective colorectal resections: a retrospective cohort analysis in consecutively operated 90 patients

Ozdemir, Suleyman, M.D ; Gulpinar, Kamil, M.D ; Ozis, S. Erpulat, M.D ; Sahli, Zafer, M.D ; Korkmaz, Atila, M.D ; Gecim, I. Ethem, M.D

England: Elsevier Ltd

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