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1-[1-[2-[(3-Chlorobenzyl)oxy]phenyl]vinyl]-1H-imidazole hydrochloride, a new potent antifungal agent

Ogata, M ; Matsumoto, H ; Hamada, Y ; Takehara, M ; Tawara, K

Journal of medicinal chemistry, 1983-05, Vol.26 (5), p.768-770 [Periódico revisado por pares]

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Título:
1-[1-[2-[(3-Chlorobenzyl)oxy]phenyl]vinyl]-1H-imidazole hydrochloride, a new potent antifungal agent
Autor: Ogata, M ; Matsumoto, H ; Hamada, Y ; Takehara, M ; Tawara, K
Assuntos: Administration, Topical ; Animals ; Antifungal Agents ; Arthrodermataceae - drug effects ; Candida - drug effects ; Guinea Pigs ; Imidazoles - pharmacology
É parte de: Journal of medicinal chemistry, 1983-05, Vol.26 (5), p.768-770
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: The synthesis and antifungal properties of 1-[1-[2-[(3-chlorobenzyl)oxy]phenyl]vinyl]-1H-imidazole hydrochloride (1 . HCl) are described. Topical application of cream and gel formulation of 1 . HCl showed high efficacy against guinea pig dermatophytosis.
Editor: United States
Idioma: Inglês

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