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The First Identification and Complete Genome of Senecavirus A Affecting Pig with Idiopathic Vesicular Disease in China

Wu, Q. ; Zhao, X. ; Bai, Y. ; Sun, B. ; Xie, Q. ; Ma, J.

Transboundary and emerging diseases, 2017-10, Vol.64 (5), p.1633-1640 [Periódico revisado por pares]

Germany: Hindawi Limited

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Título:
The First Identification and Complete Genome of Senecavirus A Affecting Pig with Idiopathic Vesicular Disease in China
Autor: Wu, Q. ; Zhao, X. ; Bai, Y. ; Sun, B. ; Xie, Q. ; Ma, J.
Assuntos: Animals ; China - epidemiology ; Disease Outbreaks - veterinary ; Exanthema ; first identification in China ; Foot & mouth disease ; genome ; Genomes ; Hogs ; Incidence ; Infections ; Lesions ; Livestock ; Neonates ; Nucleotide sequence ; outbreak of vesicular disease ; Outbreaks ; Picornaviridae - genetics ; Picornaviridae - isolation & purification ; Picornaviridae Infections - veterinary ; Picornaviridae Infections - virology ; Polymerase chain reaction ; Senecavirus A ; Stomatitis ; Swine ; Swine Diseases - epidemiology ; Swine vesicular disease ; Swine Vesicular Disease - epidemiology ; Swine Vesicular Disease - virology ; Vesicular exanthema of swine ; Viruses
É parte de: Transboundary and emerging diseases, 2017-10, Vol.64 (5), p.1633-1640
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Summary Senecavirus A (SVA) infection was recently confirmed in pigs in Brazil. In March, 2015, an outbreak of vesicular disease occurred in Guangdong, China, characterized by vesicular lesions in sows and acute death of neonatal piglets. Cumulative incidence of porcine idiopathic vesicular disease in farm A was 258, which had a total number of 5500 sows. Sows in farm B displayed typical vesicular symptoms by May, 2015, which also had 5500 sows. A total of 278 and 142 of 5500 sows in farm B demonstrated lame and presented vesicles, respectively, associated with a total of 186 mortality in piglets. Routine differential diagnoses for swine vesicular disease were carried out to exclude infection with foot‐and‐mouth disease virus, swine vesicular disease virus, vesicular exanthema of swine virus and vesicular stomatitis virus. In this study, seven pairs of primer were designed to amplify the complete genome of SVA in RT‐PCR assays. Sequence alignment showed that this Chinese strain shares 94.4–97.1% sequence identity to other eight strains of SVA. This is the first report of SVA in China and provides information about the association between SVA infection and vesicular disease.
Editor: Germany: Hindawi Limited
Idioma: Inglês

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The First Identification and Complete Genome of Senecavirus A Affecting Pig with Idiopathic Vesicular Disease in China

Wu, Q. ; Zhao, X. ; Bai, Y. ; Sun, B. ; Xie, Q. ; Ma, J.

Germany: Hindawi Limited

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