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Contrast enhancement in dense breast images using the modulation transfer function

Nunes, Fátima L. S. ; Schiabel, Homero ; Benatti, Rodrigo H.

Medical physics (Lancaster), 2002-12, Vol.29 (12), p.2925-2936 [Periódico revisado por pares]

United States: American Association of Physicists in Medicine

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Título:
Contrast enhancement in dense breast images using the modulation transfer function
Autor: Nunes, Fátima L. S. ; Schiabel, Homero ; Benatti, Rodrigo H.
Assuntos: Biological and medical applications ; Computational methods ; Computer aided diagnosis ; contrast enhancement ; dense breasts ; diagnostic radiography ; digital simulation ; False Negative Reactions ; False Positive Reactions ; Humans ; Image enhancement ; image processing ; Image Processing, Computer-Assisted - methods ; Image quality ; Image scanners ; laser applications in medicine ; mammography ; Mammography - methods ; Medical image contrast ; medical image processing ; Medical imaging ; modulation transfer function ; Modulation transfer functions ; Radiation therapy equipment ; Radiography ; Radiotherapy Planning, Computer-Assisted ; ROC Curve ; Software ; transfer functions ; X-Rays
É parte de: Medical physics (Lancaster), 2002-12, Vol.29 (12), p.2925-2936
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: This work proposes a method aimed at enhancing the contrast in dense breast images in mammography. It includes a new preprocessing technique, which uses information on the modulation transfer function (MTF) of the mammographic system in the whole radiation field. The method is applied to improve the efficiency of a computer-aided diagnosis (CAD) scheme. Seventy-five regions of interest (ROIs) from dense mammograms were acquired in two pieces of equipment (a CGR Senographe 500t and a Philips Mammodiagnost) and were digitized in a Lumiscan 50 laser scanner. A computational procedure determines the effective focal spot size in each region of interest from the measured focal spot in the center for a given mammographic equipment. Using computational simulation the MTF is then calculated for each field region. A procedure that enlarges the high-frequency portion of this function is applied and a convolution between the resulting new function and the original image is performed. Both original and enhanced images were submitted to a processing procedure for detecting clustered microcalcifications in order to compare the performance for dense breast images. ROIs were divided into four groups, two for each piece of equipment—one with clustered microcalcifications and another without microcalcifications. Our results show that in about 10% of the enhanced images more signals were detected when compared to the results for the original dense breast images. This is important because the usual processing techniques used in CAD schemes present poor results when applied to dense breast images. Since the MTF method is a well-recognized tool in the evaluation of radiographic systems, this new technique could be used to associate quality assurance procedures with the processing schemes employed in CAD for mammography.
Editor: United States: American Association of Physicists in Medicine
Idioma: Inglês

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Contrast enhancement in dense breast images using the modulation transfer function

Nunes, Fátima L. S. ; Schiabel, Homero ; Benatti, Rodrigo H.

United States: American Association of Physicists in Medicine

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