Idioma:

A diplotype in the lymphotoxin alpha gene is associated with differential expression of LTA mRNA induced by Gram-positive and Gram-negative bacteria

Temple, S. E. L. ; Almeida, C. M. ; Cheong, K. Y. ; Wunderink, R. G. ; Waterer, G. W.

International Journal of Immunogenetics, 2007-06, Vol.34 (3), p.157-160 [Periódico revisado por pares]

Texto completo disponível

Citações Citado por

Título:
A diplotype in the lymphotoxin alpha gene is associated with differential expression of LTA mRNA induced by Gram-positive and Gram-negative bacteria
Autor: Temple, S. E. L. ; Almeida, C. M. ; Cheong, K. Y. ; Wunderink, R. G. ; Waterer, G. W.
Assuntos: Adult ; Escherichia coli ; Female ; Genotype ; Humans ; Leukocytes, Mononuclear - drug effects ; Leukocytes, Mononuclear - metabolism ; Lipopolysaccharides - pharmacology ; Lymphotoxin-alpha - genetics ; Male ; Polymorphism, Genetic ; Promoter Regions, Genetic ; RNA, Messenger - metabolism ; Streptococcus pneumoniae
É parte de: International Journal of Immunogenetics, 2007-06, Vol.34 (3), p.157-160
Notas: ark:/67375/WNG-C8Z92DQ2-8
istex:15A99E6BEE31A428FABB5EBA6DCD8AB92AA1F630
ArticleID:IJI674
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Summary We sequenced the lymphotoxin alpha (LTA) promoter and identified LTA10G>A in strong linkage with LTA252G>A and LTA723C>A. Stimulated cells from LTA723AA: LTA252GG:LTA10AA individuals had significantly higher LTA mRNA levels than LTA723CC:LTA252AA:LTA10GG and LTA723AA:LTA252AG:LTA10GA individuals, suggesting that this diplotype may contain a functional polymorphism explaining the observed disease associations with LTA252G>A.
Editor: Oxford, UK: Blackwell Publishing Ltd
Idioma: Inglês

Links

Voltar para lista de resultados

Anterior Resultado 9 Avançar Ir para próxima página