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Risk Factors for Acute Kidney Injury in Visceral Leishmaniasis (Kala-Azar)

Oliveira, Michelle J. C ; Silva Junior, Geraldo B ; Abreu, Krasnalhia Livia S ; Rocha, Natalia A ; Garcia, Ana Valeska V ; Franco, Luiz F. L. G ; Mota, Rosa M. S ; Liborio, Alexandre B ; Daher, Elizabeth F

The American journal of tropical medicine and hygiene, 2010-03, Vol.82 (3), p.449-453 [Periódico revisado por pares]

Deerfield, IL: ASTMH

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Título:
Risk Factors for Acute Kidney Injury in Visceral Leishmaniasis (Kala-Azar)
Autor: Oliveira, Michelle J. C ; Silva Junior, Geraldo B ; Abreu, Krasnalhia Livia S ; Rocha, Natalia A ; Garcia, Ana Valeska V ; Franco, Luiz F. L. G ; Mota, Rosa M. S ; Liborio, Alexandre B ; Daher, Elizabeth F
Assuntos: Adolescent ; Adult ; Aged ; Aged, 80 and over ; Amphotericin B - adverse effects ; Amphotericin B - therapeutic use ; Antimony Sodium Gluconate - adverse effects ; Antimony Sodium Gluconate - therapeutic use ; Antiprotozoal Agents - adverse effects ; Antiprotozoal Agents - therapeutic use ; Biological and medical sciences ; Female ; Human protozoal diseases ; Humans ; Infectious diseases ; Kidney Diseases - etiology ; Kidney Diseases - mortality ; Kidney Diseases - parasitology ; Kidneys ; Leishmaniasis, Visceral - complications ; Leishmaniasis, Visceral - mortality ; Leshmaniasis ; Male ; Medical sciences ; Meglumine - adverse effects ; Meglumine - therapeutic use ; Middle Aged ; Nephrology. Urinary tract diseases ; Organometallic Compounds - adverse effects ; Organometallic Compounds - therapeutic use ; Parasitic diseases ; Protozoal diseases ; Risk Factors ; Urinary system involvement in other diseases. Miscellaneous ; Young Adult
É parte de: The American journal of tropical medicine and hygiene, 2010-03, Vol.82 (3), p.449-453
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: The aim of this study was to investigate the factors associated with acute kidney injury (AKI) in patients with visceral leishmaniasis (VL). The study patients had a diagnosis of VL and were admitted to a tertiary hospital. A multivariate analysis was performed to analyze the risk factors for AKI. A total of 224 patients were included. The mean age was 36 +/- 15 years. AKI was observed in 33.9% of cases. Risk factors associated with AKI were male gender (odds ratio [OR] = 2.2; P = 0.03), advanced age (OR = 1.05; P < 0.001), and jaundice (OR = 2.9; P = 0.002). There was an association between amphotericin B use and AKI (OR = 18.4; P < 0.0001), whereas glucantime use was associated with lower incidence of AKI compared with amphotericin B use (OR = 0.05; P < 0.0001). Mortality was 13.3%, and it was higher in AKI patients (30.2%). Therefore, factors associated with AKI were male gender, advanced age, and jaundice. Amphotericin B was an important cause of AKI in VL.
Editor: Deerfield, IL: ASTMH
Idioma: Inglês

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Risk Factors for Acute Kidney Injury in Visceral Leishmaniasis (Kala-Azar)

Oliveira, Michelle J. C ; Silva Junior, Geraldo B ; Abreu, Krasnalhia Livia S ; Rocha, Natalia A ; Garcia, Ana Valeska V ; Franco, Luiz F. L. G ; Mota, Rosa M. S ; Liborio, Alexandre B ; Daher, Elizabeth F

Deerfield, IL: ASTMH

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