skip to main content
Idioma:

Genome-enabled prediction of indicator traits of resistance to gastrointestinal nematodes in sheep using parametric models and artificial neural networks

Freitas, L A ; Savegnago, R P ; Alves, A A C ; Stafuzza, N B ; Pedrosa, V B ; Rocha, R A ; Rosa, G J M ; Paz, C C P

Research in veterinary science, 2024-01, Vol.166, p.105099-105099, Article 105099 [Periódico revisado por pares]

England

Texto completo disponível

Citações Citado por
  • Título:
    Genome-enabled prediction of indicator traits of resistance to gastrointestinal nematodes in sheep using parametric models and artificial neural networks
  • Autor: Freitas, L A ; Savegnago, R P ; Alves, A A C ; Stafuzza, N B ; Pedrosa, V B ; Rocha, R A ; Rosa, G J M ; Paz, C C P
  • Assuntos: Animals ; Bayes Theorem ; Genome ; Genotype ; Models, Genetic ; Nematoda - genetics ; Neural Networks, Computer ; Phenotype ; Polymorphism, Single Nucleotide ; Sheep
  • É parte de: Research in veterinary science, 2024-01, Vol.166, p.105099-105099, Article 105099
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
    content type line 23
  • Descrição: This study aimed to assess the predictive ability of parametric models and artificial neural network method for genomic prediction of the following indicator traits of resistance to gastrointestinal nematodes in Santa Inês sheep: packed cell volume (PCV), fecal egg count (FEC), and Famacha© method (FAM). After quality control, the number of genotyped animals was 551 (PCV), 548 (FEC), and 565 (FAM), and 41,676 SNP. The average prediction accuracy (ACC) calculated by Pearson correlation between observed and predicted values and mean squared errors (MSE) were obtained using genomic best unbiased linear predictor (GBLUP), BayesA, BayesB, Bayesian least absolute shrinkage and selection operator (BLASSO), and Bayesian regularized artificial neural network (three and four hidden neurons, BRANN_3 and BRANN_4, respectively) in a 5-fold cross-validation technique. The average ACC varied from moderate to high according to the trait and models, ranging between 0.418 and 0.546 (PCV), between 0.646 and 0.793 (FEC), and between 0.414 and 0.519 (FAM). Parametric models presented nearly the same ACC and MSE for the studied traits and provided better accuracies than BRANN. The GBLUP, BayesA, BayesB and BLASSO models provided better accuracies than the BRANN_3 method, increasing by around 23% for PCV, and 18.5% for FEC. In conclusion, parametric models are suitable for genome-enabled prediction of indicator traits of resistance to gastrointestinal nematodes in sheep. Due to the small differences in accuracy found between them, the use of the GBLUP model is recommended due to its lower computational costs.
  • Editor: England
  • Idioma: Inglês
Links
Voltar para lista de resultados
Ir para página anteriorAnterior Resultado  4 AvançarIr para próxima página

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.