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Convalescent Plasma Antibody Levels and the Risk of Death from Covid-19

Joyner, Michael J ; Carter, Rickey E ; Senefeld, Jonathon W ; Klassen, Stephen A ; Mills, John R ; Johnson, Patrick W ; Theel, Elitza S ; Wiggins, Chad C ; Bruno, Katelyn A ; Klompas, Allan M ; Lesser, Elizabeth R ; Kunze, Katie L ; Sexton, Matthew A ; Diaz Soto, Juan C ; Baker, Sarah E ; Shepherd, John R.A ; van Helmond, Noud ; Verdun, Nicole C ; Marks, Peter ; van Buskirk, Camille M ; Winters, Jeffrey L ; Stubbs, James R ; Rea, Robert F ; Hodge, David O ; Herasevich, Vitaly ; Whelan, Emily R ; Clayburn, Andrew J ; Larson, Kathryn F ; Ripoll, Juan G ; Andersen, Kylie J ; Buras, Matthew R ; Vogt, Matthew N.P ; Dennis, Joshua J ; Regimbal, Riley J ; Bauer, Philippe R ; Blair, Janis E ; Paneth, Nigel S ; Fairweather, DeLisa ; Wright, R. Scott ; Casadevall, Arturo

The New England journal of medicine, 2021-03, Vol.384 (11), p.1015-1027 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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Título:
Convalescent Plasma Antibody Levels and the Risk of Death from Covid-19
Autor: Joyner, Michael J ; Carter, Rickey E ; Senefeld, Jonathon W ; Klassen, Stephen A ; Mills, John R ; Johnson, Patrick W ; Theel, Elitza S ; Wiggins, Chad C ; Bruno, Katelyn A ; Klompas, Allan M ; Lesser, Elizabeth R ; Kunze, Katie L ; Sexton, Matthew A ; Diaz Soto, Juan C ; Baker, Sarah E ; Shepherd, John R.A ; van Helmond, Noud ; Verdun, Nicole C ; Marks, Peter ; van Buskirk, Camille M ; Winters, Jeffrey L ; Stubbs, James R ; Rea, Robert F ; Hodge, David O ; Herasevich, Vitaly ; Whelan, Emily R ; Clayburn, Andrew J ; Larson, Kathryn F ; Ripoll, Juan G ; Andersen, Kylie J ; Buras, Matthew R ; Vogt, Matthew N.P ; Dennis, Joshua J ; Regimbal, Riley J ; Bauer, Philippe R ; Blair, Janis E ; Paneth, Nigel S ; Fairweather, DeLisa ; Wright, R. Scott ; Casadevall, Arturo
Assuntos: Adolescent ; Adult ; Aged ; Aged, 80 and over ; Algorithms ; Antibodies ; Antibodies, Viral - blood ; Coronaviridae ; Coronaviruses ; COVID-19 ; COVID-19 - immunology ; COVID-19 - mortality ; COVID-19 - therapy ; COVID-19 Serotherapy ; Death ; Decision trees ; Female ; Generalized linear models ; Hospitalization ; Humans ; Hypotheses ; Immunization, Passive ; Immunoassay ; Immunoglobulin G ; Immunoglobulin G - blood ; Laboratories ; Male ; Mechanical ventilation ; Middle Aged ; Mortality ; Pandemics ; Patients ; Plasma ; Proteins ; Registries ; Respiration, Artificial ; Retrospective Studies ; Risk Factors ; Sample size ; SARS-CoV-2 - immunology ; Severe acute respiratory syndrome coronavirus 2 ; Statistical analysis ; Time-to-Treatment ; United States - epidemiology ; Young Adult
É parte de: The New England journal of medicine, 2021-03, Vol.384 (11), p.1015-1027
Descrição: Among more than 3000 hospitalized patients with Covid-19, recipients of high-titer convalescent plasma had a lower mortality at 30 days than recipients of low-titer plasma. The effect of high-titer plasma was greatest in the subgroup of patients who were not receiving mechanical ventilation.
Editor: United States: Massachusetts Medical Society
Idioma: Inglês

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Convalescent Plasma Antibody Levels and the Risk of Death from Covid-19

United States: Massachusetts Medical Society

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