skip to main content
Idioma:
Primo Search
Clear Search Box
Search in: Busca Geral
Busca Avançada
Busca por Índices

Comprehensive Review of Cadmium Toxicity Mechanisms in Male Reproduction and Therapeutic Strategies

de Voogt, Pim

Reviews of Environmental Contamination and Toxicology Volume 258, 2021, Vol.258, p.151-193 [Periódico revisado por pares]

Switzerland: Springer International Publishing AG

Sem texto completo

Citações Citado por
  • Título:
    Comprehensive Review of Cadmium Toxicity Mechanisms in Male Reproduction and Therapeutic Strategies
  • Autor: de Voogt, Pim
  • Assuntos: Animals ; Antioxidants ; Cadmium ; Cadmium - toxicity ; Genitalia, Male ; Male ; Male reproduction ; Mechanism ; Offspring ; Oxidative Stress ; Prevention ; Reproduction ; Treatment
  • É parte de: Reviews of Environmental Contamination and Toxicology Volume 258, 2021, Vol.258, p.151-193
  • Descrição: Cadmium (Cd) has been widely studied as an environmental pollutant for many years. Numerous studies have reported that Cd exposure causes damage to the heart, liver, kidneys, and thyroid in vivo. The emerging evidence suggests that Cd exposure induces damage on male reproductive system, which is related to oxidative stress, inflammation, steroidogenesis disruption, and epigenetics. Current preclinical animal studies have confirmed a large number of proteins and intracellular signaling pathways involved in the pathological process of Cd-induced male reproductive damage and potential measures for prophylaxis and treatment, which primarily include antioxidants, anti-inflammatory agents, and essential ion supplement. However, explicit pathogenesis and effective treatments remain uncertain. This review collects data from the literatures, discusses the underlying mechanisms of Cd-induced toxicity on male reproductive function, and summarizes evidence that may provide guidance for the treatment and prevention of Cd-induced male reproductive toxicity.
  • Títulos relacionados: Reviews of Environmental Contamination and Toxicology
  • Editor: Switzerland: Springer International Publishing AG
  • Idioma: Inglês
Links
Voltar para lista de resultados

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.