Idioma:

Short-Term Outcomes after Combined Colon and Liver Resection for Synchronous Colon Cancer Liver Metastases: A Population Study

Abbott, Andrea M. ; Parsons, Helen M. ; Tuttle, Todd M. ; Jensen, Eric H.

Annals of surgical oncology, 2013-01, Vol.20 (1), p.139-147 [Periódico revisado por pares]

New York: Springer-Verlag

Texto completo disponível

Citações Citado por

Enviar para

Título:
Short-Term Outcomes after Combined Colon and Liver Resection for Synchronous Colon Cancer Liver Metastases: A Population Study
Autor: Abbott, Andrea M. ; Parsons, Helen M. ; Tuttle, Todd M. ; Jensen, Eric H.
Assuntos: Aged ; Colectomy - adverse effects ; Colonic Neoplasms - mortality ; Colonic Neoplasms - pathology ; Colonic Neoplasms - surgery ; Colorectal Cancer ; Confidence Intervals ; Female ; Hepatectomy - adverse effects ; Hepatectomy - methods ; Hospital Mortality ; Humans ; Length of Stay - statistics & numerical data ; Liver Neoplasms - mortality ; Liver Neoplasms - secondary ; Liver Neoplasms - surgery ; Male ; Medicine ; Medicine & Public Health ; Middle Aged ; Multivariate Analysis ; Odds Ratio ; Oncology ; Retrospective Studies ; Surgery ; Surgical Oncology ; Time Factors ; United States - epidemiology
É parte de: Annals of surgical oncology, 2013-01, Vol.20 (1), p.139-147
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Introduction The timing of surgical resection for stage IV colon cancer with liver metastasis and the safety of simultaneous colon and liver resection remains controversial. The purpose of our study was to evaluate short-term outcomes after combined colon and liver resection (CCLR) versus colon resection (CR) or liver resection alone (LR) using a population database. Methods The National Inpatient Sample was used to select patients who had surgery for colon cancer from 2002 to 2006. We evaluated for in-hospital morbidity, mortality, and prolonged length of stay (PLOS). Our analysis was done using design-weighted unadjusted analysis and logistic regression. Results We identified 361,096 patients during our study period (CCLR 3,625; CR 322,286; LR 35,185). CCLR was not associated with an increased risk of complications (odds ratio (OR) 1.12; 95 % confidence interval (CI) 0.94–1.33; P = 0.21) or PLOS (OR 1.19; 95 % CI 0.99–1.4; P = 0.06) compared with CR. In-hospital mortality occurred in 3.5 % of patients who underwent CCLR and was not significantly associated with mortality compared with CR alone (OR 1.17; 95 % CI 0.79–1.74; P = 0.43). Liver lobectomy with CR was associated with a PLOS and a trend toward increased morbidity and mortality. Significant predictors of complications, mortality, and PLOS included: age >70 years, male gender, nonprivate health insurance, and Elixhauser score >1. Conclusions CCLR with limited liver resection can be performed with similar morbidity and mortality to colectomy alone. For patients who require hepatic lobectomy, however, strong consideration should be given to a staged approach.
Editor: New York: Springer-Verlag
Idioma: Inglês

Links

View this record in MEDLINE/PubMed

Voltar para lista de resultados

Realização: Logos de Redes Sociais:

Short-Term Outcomes after Combined Colon and Liver Resection for Synchronous Colon Cancer Liver Metastases: A Population Study

Abbott, Andrea M. ; Parsons, Helen M. ; Tuttle, Todd M. ; Jensen, Eric H.

New York: Springer-Verlag

Buscando em bases de dados remotas. Favor aguardar.