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Attending COVID-19 patients during the first wave of the pandemic in a Medium Stay Hospital: Variables associated with mortality in hospitalized patients in an acute situation

Carrillo Alcalá, M Elena ; Minaya Saiz, Jesús

Revista española de geriatría y gerontología, 2021-11, Vol.56 (6), p.334-342 [Periódico revisado por pares]

Spain

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  • Título:
    Attending COVID-19 patients during the first wave of the pandemic in a Medium Stay Hospital: Variables associated with mortality in hospitalized patients in an acute situation
  • Autor: Carrillo Alcalá, M Elena ; Minaya Saiz, Jesús
  • Assuntos: Comorbidity ; COVID-19 ; Hospitals ; Humans ; Pandemics ; SARS-CoV-2
  • É parte de: Revista española de geriatría y gerontología, 2021-11, Vol.56 (6), p.334-342
  • Notas: ObjectType-Article-1
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  • Descrição: Spain has been one of the countries most affected by the SARS-CoV-2 pandemic. The objective of this study is to describe the characteristics of the patients treated for COVID-19 at Guadarrama Hospital and to identify the associated mortality factors in those admitted in an acute situation. Retrospective observational study of COVID-19 patients admitted from 3/15 to 5/15/2020. Sociodemographic, mental, functional, analytical, clinical, radiological and therapeutic variables were collected. Factors associated with mortality were analysed using a bivariate and multivariate study. Two hundred eleven patients were included: 102 (48.3%) in an acute situation and 109 (51.7%) in the convalescent phase, the median (interquartile range) age was 82 (72, 85) years. The most frequent symptoms were fever, cough and respiratory failure. The 89.9% had pneumonia. An acute mortality rate of 26.5% (27/102) was detected and the associated factors were: respiratory failure (P 0.002), Charlson index (ChI)≥3 (P<0.001), CURB≥2 (P 0.011), low SatO /FiO ratio (<0.001), elevated urea (P<0.001) and creatinine (P 0.036), hypoproteinemia (P 0.037) and age (P<0.018). The deceased had a worse functional situation than the survivors (P 0.025). In the multivariate analysis, SatO /FiO ratio (OR: 2.23; 95% CI: 1.07-4.63; P 0.031) and ChI≥3 (OR: 4.25; 95% CI: 1.06-17.04; P 0.041) were independent factors of mortality. The COVID-19 patients treated were mostly severe cases. The variables associated with mortality were age, respiratory failure, comorbidity, kidney failure, and malnutrition. Respiratory failure and comorbidity outweigh age as independent risk factors for mortality.
  • Editor: Spain
  • Idioma: Espanhol
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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