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MacGlashan, Donald

Journal of allergy and clinical immunology, 2019-08, Vol.144 (2), p.623 [Periódico revisado por pares]

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Autor: MacGlashan, Donald
Assuntos: Histamine ; Immunoglobulins
É parte de: Journal of allergy and clinical immunology, 2019-08, Vol.144 (2), p.623
Descrição: Dr Kaplan1 is correct to note that my study's use of 25% serum placed a partial limit on sensitivity because it was possible that either undiluted serum was necessary to observe some function or that additional components, such as complement, were needed to drive or augment the reaction. Notably, not all release induced by serum appears attributable to signaling activity through the high-affinity IgE receptor. The induced histamine release was not inhibited with potent agents that operate on FcεRI-mediated signaling.
Editor: St. Louis: Elsevier Limited
Idioma: Inglês

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