skip to main content
Idioma:
Primo Search
Clear Search Box
Search in: Busca Geral
Busca Avançada
Busca por Índices
Tipo de recurso Mostra resultados com: Mostra resultados com: Índice

Serial monitoring of pancreatic lipase immunoreactivity, C‐reactive protein, abdominal ultrasonography, and clinical severity in dogs with suspected pancreatitis

Mitchell, Leslie ; Wang, Sichao ; Lawver, Jody ; Cridge, Harry

Journal of veterinary internal medicine, 2024-03, Vol.38 (2), p.987-994 [Periódico revisado por pares]

Hoboken, USA: John Wiley & Sons, Inc

Texto completo disponível

Citações Citado por
  • Título:
    Serial monitoring of pancreatic lipase immunoreactivity, C‐reactive protein, abdominal ultrasonography, and clinical severity in dogs with suspected pancreatitis
  • Autor: Mitchell, Leslie ; Wang, Sichao ; Lawver, Jody ; Cridge, Harry
  • Assuntos: Abdomen ; Acute Disease ; Animals ; Biomarkers ; C-Reactive Protein ; Dog Diseases - diagnostic imaging ; Dogs ; Enrollments ; Histopathology ; immunoassay ; Internal medicine ; Laboratories ; Lipase ; Medicine ; monitoring ; pancreas ; Pancreas - diagnostic imaging ; Pancreatitis ; Pancreatitis - diagnostic imaging ; Pancreatitis - veterinary ; PLI ; Proteins ; SMALL ANIMAL ; Spec cPL ; Ultrasonic imaging ; Ultrasonography - veterinary ; ultrasound
  • É parte de: Journal of veterinary internal medicine, 2024-03, Vol.38 (2), p.987-994
  • Notas: ObjectType-Article-2
    SourceType-Scholarly Journals-1
    ObjectType-Undefined-1
    ObjectType-Feature-3
    content type line 23
  • Descrição: Background Diagnosis of pancreatitis is based on clinical signs, pancreatic lipase immunoreactivity (cPLI), and abdominal ultrasonography (AUS). Diagnostic discrepancies exist between test results which might be related to differences in the timeline for resolution of these abnormalities after pancreatic injury. Hypothesis/Objectives To evaluate disease severity, ultrasonographic findings, and serum biomarkers of pancreatitis in dogs over a period of 28‐days. Animals Sixteen client‐owned dogs with a clinical suspicion for acute pancreatitis based on history/physical examination, an abnormal SNAP cPLI, and ultrasonographic evidence of pancreatitis. Methods Prospective observational study. Clinical severity (modified clinical activity index [MCAI]), cPLI, C‐reactive protein (CRP), and AUS were evaluated at days 0, 2, 7, and 28. Owner assessed overall health (OH) was noted. Dogs were stratified into baseline cPLI ≥400 μg/L vs <400 μg/L groups for reporting. Results The median CRP, MCAI, and OH were 111.9 mg/L, 10, and 4/10 respectively in the cPLI ≥400 μg/L group. The median CRP, MCAI, and OH were 58.0 mg/L, 6, and 6/10 respectively in the cPLI <400 μg/L group. None of these variables were significantly different between groups. Most dogs (4/5) in the cPLI <400 μg/L group had a history of suspected pancreatitis (ie, suspect acute on chronic disease). cPLI and MCAI rapidly decreased in dogs with a baseline cPLI ≥400 μg/L, whereas sonographic evidence of pancreatitis persisted for a longer time period. Conclusions and Clinical Importance Ultrasonographic evidence of pancreatitis in the absence of overt clinical or biochemical abnormalities might represent a resolving injury rather than active disease.
  • Editor: Hoboken, USA: John Wiley & Sons, Inc
  • Idioma: Inglês
Links
Voltar para lista de resultados
Ir para página anteriorAnterior Resultado  6 AvançarIr para próxima página

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.