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Cost-effectiveness of the introduction of specialized oral care with laser therapy in hematopoietic stem cell transplantation

Bezinelli, Letícia Mello ; de Paula Eduardo, Fernanda ; da Graça Lopes, Roberta Marques ; Biazevic, Maria Gabriela Haye ; de Paula Eduardo, Carlos ; Correa, Luciana ; Hamerschlak, Nelson ; Michel-Crosato, Edgard

Hematological oncology, 2014-03, Vol.32 (1), p.31-39 [Periódico revisado por pares]

England: Blackwell Publishing Ltd

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Título:
Cost-effectiveness of the introduction of specialized oral care with laser therapy in hematopoietic stem cell transplantation
Autor: Bezinelli, Letícia Mello ; de Paula Eduardo, Fernanda ; da Graça Lopes, Roberta Marques ; Biazevic, Maria Gabriela Haye ; de Paula Eduardo, Carlos ; Correa, Luciana ; Hamerschlak, Nelson ; Michel-Crosato, Edgard
Assuntos: Adult ; Aged ; Allografts - economics ; Anti-Bacterial Agents - administration & dosage ; Anti-Bacterial Agents - economics ; Anti-Bacterial Agents - therapeutic use ; Antibiotic Prophylaxis - economics ; Antifungal Agents - administration & dosage ; Antifungal Agents - economics ; Antifungal Agents - therapeutic use ; Antineoplastic Combined Chemotherapy Protocols - economics ; Antineoplastic Combined Chemotherapy Protocols - therapeutic use ; Brazil ; Case-Control Studies ; Cost-Benefit Analysis ; Dentists - economics ; Drug Costs ; Female ; hematopoietic stem cell transplantation ; Hematopoietic Stem Cell Transplantation - adverse effects ; Hematopoietic Stem Cell Transplantation - economics ; Hospital Costs ; Hospitalization - economics ; Humans ; Immunocompromised Host ; Immunosuppressive Agents - adverse effects ; Immunosuppressive Agents - economics ; Immunosuppressive Agents - therapeutic use ; low-level laser therapy ; Low-Level Light Therapy - economics ; Low-Level Light Therapy - methods ; Male ; Middle Aged ; Myeloablative Agonists - economics ; Myeloablative Agonists - therapeutic use ; Narcotics - economics ; Narcotics - therapeutic use ; Opportunistic Infections - economics ; Opportunistic Infections - etiology ; Opportunistic Infections - prevention & control ; oral hygiene ; Oral Hygiene - economics ; Oral Hygiene - methods ; oral mucositis ; Parenteral Nutrition - economics ; Patient Care Team ; Retrospective Studies ; Self Care - economics ; Stomatitis - economics ; Stomatitis - etiology ; Stomatitis - prevention & control ; Stomatitis - therapy ; Transplantation Conditioning - adverse effects ; Transplantation Conditioning - economics ; Transplantation, Autologous - economics
É parte de: Hematological oncology, 2014-03, Vol.32 (1), p.31-39
Notas: ArticleID:HON2050
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SourceType-Scholarly Journals-1
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Descrição: Oral mucositis (OM) is one of the side effects of hematopoietic stem cell transplantation (HSCT), resulting in major morbidity. The aim of this study was to determine the cost‐effectiveness of the introduction of a specialized oral care program including laser therapy in the care of patients receiving HSCT with regard to morbidity associated with OM. Clinical information was gathered on 167 patients undergoing HSCT and divided according to the presence (n = 91) or absence (n = 76) of laser therapy and oral care. Cost analysis included daily hospital fees, parenteral nutrition (PN) and prescription of opioids. It was observed that the group without laser therapy (group II) showed a higher frequency of severe degrees of OM (relative risk = 16.8, 95% confidence interval −5.8 to 48.9, p < 0.001), with a significant association between this severity and the use of PN (p = 0.001), prescription of opioids (p < 0.001), pain in the oral cavity (p = 0.003) and fever > 37.8°C (p = 0.005). Hospitalization costs in this group were up to 30% higher. The introduction of oral care by a multidisciplinary staff including laser therapy helps reduce morbidity resulting from OM and, consequently, helps minimize hospitalization costs associated with HSCT, even considering therapy costs. Copyright © 2013 John Wiley & Sons, Ltd.
Editor: England: Blackwell Publishing Ltd
Idioma: Inglês

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Cost-effectiveness of the introduction of specialized oral care with laser therapy in hematopoietic stem cell transplantation

Bezinelli, Letícia Mello ; de Paula Eduardo, Fernanda ; da Graça Lopes, Roberta Marques ; Biazevic, Maria Gabriela Haye ; de Paula Eduardo, Carlos ; Correa, Luciana ; Hamerschlak, Nelson ; Michel-Crosato, Edgard

England: Blackwell Publishing Ltd

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