skip to main content
Visitante
Meu Espaço
Minha Conta
Sair
Identificação
This feature requires javascript
Tags
Revistas Eletrônicas (eJournals)
Livros Eletrônicos (eBooks)
Bases de Dados
Bibliotecas USP
Ajuda
Ajuda
Idioma:
Inglês
Espanhol
Português
This feature required javascript
This feature requires javascript
Primo Search
Busca Geral
Busca Geral
Acervo Físico
Acervo Físico
Produção Intelectual da USP
Produção USP
Search For:
Clear Search Box
Search in:
Busca Geral
Or hit Enter to replace search target
Or select another collection:
Search in:
Busca Geral
Busca Avançada
Busca por Índices
This feature requires javascript
This feature requires javascript
Telocytes in Inflammatory Gynaecologic Diseases and Infertility
Yang, Xiao-Jun
Advances in experimental medicine and biology, 2016, Vol.913, p.263-285
[Periódico revisado por pares]
Singapore: Springer Singapore Pte. Limited
Sem texto completo
Citações
Citado por
Serviços
Detalhes
Resenhas & Tags
Nº de Citações
This feature requires javascript
Enviar para
Adicionar ao Meu Espaço
Remover do Meu Espaço
E-mail (máximo 30 registros por vez)
Imprimir
Link permanente
Referência
EasyBib
EndNote
RefWorks
del.icio.us
Exportar RIS
Exportar BibTeX
This feature requires javascript
Título:
Telocytes in Inflammatory Gynaecologic Diseases and Infertility
Autor:
Yang, Xiao-Jun
Assuntos:
Acute salpingitis (AS)
;
Animals
;
Antigens, CD34 - genetics
;
Antigens, CD34 - metabolism
;
Biomarkers - metabolism
;
Cellular biology
;
Cytokines
;
Endometriosis
;
Endometriosis - complications
;
Endometriosis - genetics
;
Endometriosis - metabolism
;
Endometriosis - pathology
;
Enzyme
;
Female
;
Fertility disorder
;
Fibrosis
;
Gene Expression
;
Humans
;
Immune response
;
Immunoregulation
;
Infertility
;
Infertility, Female - complications
;
Infertility, Female - genetics
;
Infertility, Female - metabolism
;
Infertility, Female - pathology
;
Inflammation
;
Inflammatory factors
;
Interstitial cells
;
Macrophage activation
;
Medical research
;
Mice
;
Oviduct
;
Pelvic inflammatory disease
;
Pregnancy
;
Pregnancy, Ectopic - genetics
;
Pregnancy, Ectopic - metabolism
;
Pregnancy, Ectopic - pathology
;
Rat model
;
Rats
;
Salpingitis - complications
;
Salpingitis - genetics
;
Salpingitis - metabolism
;
Salpingitis - pathology
;
Stromal cells
;
Telocytes - metabolism
;
Telocytes - pathology
;
Tissue Adhesions - complications
;
Tissue Adhesions - genetics
;
Tissue Adhesions - metabolism
;
Tissue Adhesions - pathology
;
Tubal ectopic pregnancy
;
Tubal factor infertility
;
Uterine telocytes
;
Uterus - metabolism
;
Uterus - pathology
;
Vimentin - genetics
;
Vimentin - metabolism
É parte de:
Advances in experimental medicine and biology, 2016, Vol.913, p.263-285
Notas:
ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
Descrição:
Women suffered with inflammatory gynecologic diseases, such as endometriosis (EMs) and acute salpingitis (AS) often complained of sub- or infertility, even in those women without obvious macroscopic anatomical pelvic abnormalities also have unexplained infertility. Generally, besides the well-known impairment of classically described oviduct cells caused by inflammatory diseases, such as the ciliated cells, fibroblasts and myofibroblasts, the involvement of the newly identified telocytes (TCs) in disease-affected oviduct tissues and potential pathophysiological roles in fertility problems remain unknown. In this chapter, TCs was investigated in rat model of EMs- and AS-affected oviduct tissues. Results showed inflammation and ischaemia-induced extensive ultrastructural damages of TCs both in cellular body and prolongations, with obvious TCs loss and interstitial fibrotic remodelling. Such in vivo pathological alterations might contribute to structural and functional abnormalities of oviduct tissue and potentially engaged in sub- or infertility. And especially, TCs connected to various activated immunocytes in both normal and diseased tissues, thus might participate in local immunoregulation (either repression or activation) and serve a possible explanation for immune-mediated pregnancy failure. Then, in vitro cell co-culture study showed that uterine TC conditioned media (TCM) can activate mouse peritoneal macrophages and subsequently trigger its cytokine secretion, thus providepreliminary evidence that, TCs are not simply innocent bystanders, but are instead potential functional players in local immunoregulatory and immunosurveillance.
Títulos relacionados:
Advances in Experimental Medicine and Biology
Editor:
Singapore: Springer Singapore Pte. Limited
Idioma:
Inglês
Links
View this record in MEDLINE/PubMed
This feature requires javascript
This feature requires javascript
Voltar para lista de resultados
This feature requires javascript
This feature requires javascript
Buscando em bases de dados remotas. Favor aguardar.
Buscando por
em
scope:(USP_VIDEOS),scope:("PRIMO"),scope:(USP_FISICO),scope:(USP_EREVISTAS),scope:(USP),scope:(USP_EBOOKS),scope:(USP_PRODUCAO),primo_central_multiple_fe
Mostrar o que foi encontrado até o momento
This feature requires javascript
This feature requires javascript