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Insights into the Microbial Composition of Intratumoral, Reproductive Tract, and Gut Microbiota in Ovarian Cancer Patients

Zhou, Qian ; Meng, Qingren

Advances in experimental medicine and biology, 2024, Vol.1452, p.107-118 [Periódico revisado por pares]

Cham: Springer International Publishing

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  • Título:
    Insights into the Microbial Composition of Intratumoral, Reproductive Tract, and Gut Microbiota in Ovarian Cancer Patients
  • Autor: Zhou, Qian ; Meng, Qingren
  • Assuntos: Female ; Gastrointestinal Microbiome ; Genitalia, Female - microbiology ; Gut microbiota ; Humans ; Immune regulation ; Microbiota ; Ovarian cancer ; Ovarian Neoplasms - immunology ; Ovarian Neoplasms - microbiology ; Reproductive tract microbiota ; Tumor microbiota
  • É parte de: Advances in experimental medicine and biology, 2024, Vol.1452, p.107-118
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
    ObjectType-Review-3
    content type line 23
  • Descrição: According to the latest global cancer data, ovarian cancer is the deadliest among all gynecological malignant tumors and ranks fifth in terms of mortality. Its etiology and pathogenesis are unknown, and the 5-year survival rate of patients with advanced ovarian cancer is only 40% (Sung et al. CA Cancer J Clin 71:209–49, 2021). Recent research has shown that the human microbiota plays a crucial role in the development and progression of tumors, including ovarian cancer. Numerous studies have highlighted the complex connections between the reproductive tract microbiota, intestinal microbiota, and ovarian cancer (Jacobson et al. PeerJ 9:e11574, 2021). Therefore, this chapter will delve into composition, function, and the correlation between microbiota and immunity in the field of ovarian cancer microbiota, as well as the potential of bacteria in therapeutics and diagnostics of ovarian cancer.
  • Títulos relacionados: Advances in Experimental Medicine and Biology
  • Editor: Cham: Springer International Publishing
  • Idioma: Inglês
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