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The Beneluxa Initiative domain task force health technology assessment: a comparison of member countries’ past health technology assessments

Vreman, Rick A. ; van Hoof, Daan ; Nachtnebel, Anna ; Daems, Joël ; van de Casteele, Marc ; Fogarty, Emer ; Adams, Roisin ; Timmers, Lonneke

International journal of technology assessment in health care, 2023-06, Vol.39 (1), p.e44-e44, Article e44 [Periódico revisado por pares]

New York, USA: Cambridge University Press

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  • Título:
    The Beneluxa Initiative domain task force health technology assessment: a comparison of member countries’ past health technology assessments
  • Autor: Vreman, Rick A. ; van Hoof, Daan ; Nachtnebel, Anna ; Daems, Joël ; van de Casteele, Marc ; Fogarty, Emer ; Adams, Roisin ; Timmers, Lonneke
  • Assuntos: Assessment ; Collaboration ; Comparative analysis ; Drugs ; Health technology assessment ; Reimbursement ; Technology assessment
  • É parte de: International journal of technology assessment in health care, 2023-06, Vol.39 (1), p.e44-e44, Article e44
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
    content type line 23
  • Descrição: This study aimed to compare assessments between Beneluxa Initiative member countries' assessments and identify alignments and divergences. A retrospective comparative analysis was performed that investigated (i) number and type of assessed indications (for Austria (AT), Belgium (BE), Ireland (IE), and the Netherlands (NL)); (ii) added benefit conclusions (for BE, IE, and NL); and (iii) the main arguments underlying differences in conclusions (for BE, IE, and NL). Data were retrieved directly from agency representatives and from public HTA reports. European Medicines Agency approved indications were included for drugs assessed between 2016 and 2020, excluding veterinary drugs, generics, and biosimilars. Only 44 (10 percent) of the 444 included indications were assessed by all four member countries. Between any pair of two countries, the overlap was higher, from 63 (AT-NL) to 188 (BE-IE). Added benefit conclusions matched exactly in 62-74 percent of the indications, depending on the countries compared. In the remaining cases, most often a difference of one added benefit level was observed (e.g., higher vs. equal relative effect). Contradictory outcomes were very rare: only three cases were observed (lower vs. higher effect). When assessing the underlying arguments for seven cases with different outcomes, differences were attributable to slight differences in weighing of evidence and uncertainties rather than disagreement on aspects within the assessment itself. Despite high variability in European HTA procedures, collaboration on HTA between the Beneluxa Initiative member countries is very feasible and would likely not result in added benefit conclusions that would be very different from added benefit conclusions in national procedures.
  • Editor: New York, USA: Cambridge University Press
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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