The Insults of Illicit Drug Use on Male Fertility

• Autor: Fronczak, Carolyn M. ; Kim, Edward D. ; Barqawi, Al B.
• Assuntos: Adolescent ; Adult ; Anabolic Agents - adverse effects ; anabolic‐androgenic steroids ; Analgesics, Opioid - adverse effects ; Androgens - adverse effects ; Animals ; Biological and medical sciences ; Birth control ; cocaine ; Cocaine - adverse effects ; epidemiology ; Fertility - drug effects ; Fundamental and applied biological sciences. Psychology ; Gynecology. Andrology. Obstetrics ; human and animal studies ; Humans ; illicit drugs ; Infertility, Male - chemically induced ; Infertility, Male - epidemiology ; Male ; male factor infertility ; Male genital diseases ; Male infertility ; Mammalian male genital system ; marijuana ; Marijuana Abuse - complications ; Medical sciences ; Methamphetamine - adverse effects ; methamphetamines ; Middle Aged ; N-Methyl-3,4-methylenedioxyamphetamine - adverse effects ; Neuropharmacology ; opioid narcotics ; Pharmacology. Drug treatments ; Prevalence ; Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer ; Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) ; Psychology. Psychoanalysis. Psychiatry ; Psychopharmacology ; Rats ; Spermatogenesis - drug effects ; Sterility. Assisted procreation ; Street Drugs - adverse effects ; subfertility ; substance abuse ; Substance-Related Disorders - epidemiology ; Testosterone - adverse effects ; Testosterone - analogs & derivatives ; United States - epidemiology ; Vertebrates: reproduction
• É parte de: Journal of andrology, 2012-07, Vol.33 (4), p.515-528
• Notas: ObjectType-Article-2
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• Descrição: : One‐third of infertile couples may have a male factor present. Illicit drug use can be an important cause of male factor infertility and includes use of anabolic‐androgenic steroids, marijuana, opioid narcotics, cocaine, and methamphetamines. The use of these illicit drugs is common in the United States, with a yearly prevalence rate for any drug consistently higher in males compared with females. We aim to provide a review of recent literature on the prevalence and effects of illicit drug use on male fertility and to aid health professionals when counseling infertile men whose social history suggests illicit drug use. Anabolic‐androgenic steroids, marijuana, cocaine, methamphetamines, and opioid narcotics all negatively impact male fertility, and adverse effects have been reported on the hypothalamic‐pituitary‐testicular axis, sperm function, and testicular structure. The use of illicit drugs is prevalent in our society and likely adversely impacting the fertility of men who abuse drugs.
  
• Editor: Oxford, UK: Blackwell Publishing Ltd
  
• Idioma: Inglês