skip to main content
Primo Search
Search in: Busca Geral

Enigma of Y chromosome degeneration: Neo-Y and Neo-X chromosomes of Drosophila miranda a model for sex chromosome evolution

Steinemann, Manfred ; Steinemann, Sigrid

Mutation and Evolution, p.409-420 [Periódico revisado por pares]

Dordrecht: Springer Netherlands

Sem texto completo

Citações Citado por
  • Título:
    Enigma of Y chromosome degeneration: Neo-Y and Neo-X chromosomes of Drosophila miranda a model for sex chromosome evolution
  • Autor: Steinemann, Manfred ; Steinemann, Sigrid
  • Assuntos: Drosophila ; evolution ; sex chromosomes ; Y chromosome degeneration ; Y chromosome mutations
  • É parte de: Mutation and Evolution, p.409-420
  • Descrição: Y chromosome degeneration is characterized by structural changes in the chromosome architecture and expansion of genetic inertness along the y chromosome. It is generally assumed that the heteromorphic sex chromosome pair has developed from a pair of homologues. Several models have been suggested. We use the unique situation of the secondary sex chromosome pair, neo-Y and neo-X (X2), in Drosophila miranda to analyze molecular mechanisms involved in the evolutionary processes of Y chromosome degeneration. Due to the fusion of one of the autosomes to the y chromosome (about 2 Mya), a neo- Y chromosome and a neo-X chromosome, designated X2, were formed. Thus, formerly autosomal genes are inherited now on a pair of sex chromosomes in D. miranda. Analyzing DNA sequences from the X2 and neo-Y region, we observed a massive accumulation of DNA insertions on the neo-Y chromosome. From the analysis of several insertion elements, we present compelling evidence that the first step in Y chromosome degeneration is driven by the accumulation of transposable elements, especially retrotransposons. An enrichment of these elements along an evolving Y chromosome could account for the switch from a euchromatic into a heterochromatic chromatin structure.
  • Títulos relacionados: Contemporary Issues in Genetics and Evolution
  • Editor: Dordrecht: Springer Netherlands
  • Idioma: Inglês

Buscando em bases de dados remotas. Favor aguardar.