Afatinib versus methotrexate as second-line treatment in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck progressing on or after platinum-based therapy (LUX-Head & Neck 1): an open-label, randomised phase 3 trial

Machiels, Jean-Pascal H, Prof ; Haddad, Robert I, MD ; Fayette, Jérôme, MD ; Licitra, Lisa F, MD ; Tahara, Makoto, MD ; Vermorken, Jan B, Prof ; Clement, Paul M, Prof ; Gauler, Thomas, MD ; Cupissol, Didier, MD ; Grau, Juan José, MD ; Guigay, Joël, Prof ; Caponigro, Francesco, MD ; de Castro, Gilberto, PhD ; de Souza Viana, Luciano, MD ; Keilholz, Ulrich, Prof ; del Campo, Joseph M, MD ; Cong, Xiuyu Julie, PhD ; Ehrnrooth, Eva, MD ; Cohen, Ezra E W, MD

The lancet oncology, 2015-05, Vol.16 (5), p.583-594 [Periódico revisado por pares]

England: Elsevier Ltd

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