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18 - Male Reproductive System

Knoblaugh, Sue ; True, Lawrence

Comparative Anatomy and Histology, 2012, p.285-308

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Título:
18 - Male Reproductive System
Autor: Knoblaugh, Sue ; True, Lawrence
Assuntos: Epithelium ; histology ; lobe ; male ; prostate ; secretions ; sperm ; testes ; urogenital
É parte de: Comparative Anatomy and Histology, 2012, p.285-308
Descrição: It is important for researchers and pathologists to know the normal anatomy and histology of both the mouse and the human male urogenital tract and to understand the anatomical differences between mouse and human. Genetically engineered mouse models can exhibit changes not seen in the human. The prostate gland exemplifies this point. The mouse prostate is divided into four lobes, where each lobe is histologically distinct. Conversely, the human prostate is a single organ without lobes. The mouse also contains additional accessory sex glands that are not found in the human. Consequently, these glands in mouse should not be interpreted as an abnormal finding. Histologic characteristics are important to understanding the phenotype of mouse models of human disease. A basic understanding of the normal histology of the urogenital organs of mouse and human is essential for proper interpretation and characterization of mouse models of disease.
Editor: Elsevier Inc
Idioma: Inglês

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