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In a randomized trial, the live attenuated tetravalent dengue vaccine TV003 is well-tolerated and highly immunogenic in subjects with flavivirus exposure prior to vaccination

Whitehead, Stephen S ; Durbin, Anna P ; Pierce, Kristen K ; Elwood, Dan ; McElvany, Benjamin D ; Fraser, Ellen A ; Carmolli, Marya P ; Tibery, Cecilia M ; Hynes, Noreen A ; Jo, Matthew ; Lovchik, Janece M ; Larsson, Catherine J ; Doty, Elena A ; Dickson, Dorothy M ; Luke, Catherine J ; Subbarao, Kanta ; Diehl, Sean A ; Kirkpatrick, Beth D Messer, William B

PLoS neglected tropical diseases, 2017-05, Vol.11 (5), p.e0005584-e0005584 [Periódico revisado por pares]

United States: Public Library of Science

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Título:
In a randomized trial, the live attenuated tetravalent dengue vaccine TV003 is well-tolerated and highly immunogenic in subjects with flavivirus exposure prior to vaccination
Autor: Whitehead, Stephen S ; Durbin, Anna P ; Pierce, Kristen K ; Elwood, Dan ; McElvany, Benjamin D ; Fraser, Ellen A ; Carmolli, Marya P ; Tibery, Cecilia M ; Hynes, Noreen A ; Jo, Matthew ; Lovchik, Janece M ; Larsson, Catherine J ; Doty, Elena A ; Dickson, Dorothy M ; Luke, Catherine J ; Subbarao, Kanta ; Diehl, Sean A ; Kirkpatrick, Beth D
Messer, William B
Assuntos: Adolescent ; Adult ; Antibodies ; Antibodies, Neutralizing - blood ; Antibodies, Viral - blood ; Antibody response ; Aquatic insects ; Arthropods ; Authorship ; Biology and Life Sciences ; Defence mechanisms ; Dengue ; Dengue fever ; Dengue hemorrhagic fever ; Dengue Vaccines - administration & dosage ; Dengue Vaccines - adverse effects ; Dengue Vaccines - immunology ; Disease control ; Diseases ; Double-Blind Method ; Drug dosages ; Drug-Related Side Effects and Adverse Reactions - epidemiology ; Drug-Related Side Effects and Adverse Reactions - pathology ; Encephalitis ; Exanthema ; Exposure ; Female ; Fever ; Flavivirus Infections - immunology ; Frequency ; Human diseases ; Human subjects ; Humans ; Immune response ; Immune system ; Immunity ; Immunogenicity ; Immunoglobulins ; Immunology ; Infections ; Infectious diseases ; Laboratories ; Male ; Medicine ; Medicine and Health Sciences ; Middle Aged ; Neutralizing ; Prevention ; Public health ; Serotypes ; Tropical diseases ; Vaccination ; Vaccines ; Vaccines, Attenuated - administration & dosage ; Vaccines, Attenuated - adverse effects ; Vaccines, Attenuated - immunology ; Vector-borne diseases ; Viral diseases ; Viral replication ; Viremia ; Viruses ; Young Adult
É parte de: PLoS neglected tropical diseases, 2017-05, Vol.11 (5), p.e0005584-e0005584
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These authors share first authorship on this work.
The authors have declared that no competing interests exist.
Conceptualization: SSW APD BDK.Data curation: APD DMD.Formal analysis: SSW APD SAD KKP MPC DMD BDK.Funding acquisition: SSW APD KS BDK.Investigation: APD KKP DE BDM EAF MPC CMT NAH MJ JML CJLa EAD.Methodology: APD KKP NAH CJLa BDK.Project administration: APD CJLu BDK.Supervision: APD BDK.Validation: SSW APD SAD KKP MPC DMD BDK.Visualization: APD SAD DMD BDK.Writing – original draft: SAD BDK.Writing – review & editing: SSW APD SAD BDK.
Descrição: ClinicalTrials.gov NCT01506570.
Editor: United States: Public Library of Science
Idioma: Inglês

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In a randomized trial, the live attenuated tetravalent dengue vaccine TV003 is well-tolerated and highly immunogenic in subjects with flavivirus exposure prior to vaccination

United States: Public Library of Science

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