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Electro-oxidative Intermolecular Allylic C(sp3)–H Aminations

Wang, Yulei ; Lin, Zhipeng ; Oliveira, João C. A ; Ackermann, Lutz

Journal of organic chemistry, 2021-11, Vol.86 (22), p.15935-15945 [Periódico revisado por pares]

American Chemical Society

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  • Título:
    Electro-oxidative Intermolecular Allylic C(sp3)–H Aminations
  • Autor: Wang, Yulei ; Lin, Zhipeng ; Oliveira, João C. A ; Ackermann, Lutz
  • É parte de: Journal of organic chemistry, 2021-11, Vol.86 (22), p.15935-15945
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
    content type line 23
  • Descrição: The oxidative intermolecular nitrogenation of C­(sp3)–H bonds represents one of the most straightforward strategies to construct nitrogen-containing molecules. However, a sacrificial chemical oxidant is generally required. Herein, we describe electrochemical oxidative intermolecular allylic C­(sp3)–H aminations in an undivided cell by electric current. The cross-dehydrogenative amination proceeded efficiently with ample scope under metal- and chemical oxidant-free reaction conditions, giving molecular H2 as the only byproduct.
  • Editor: American Chemical Society
  • Idioma: Inglês

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