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Neurobiology of rodent self-grooming and its value for translational neuroscience

Kalueff, Allan V ; Stewart, Adam Michael ; Song, Cai ; Berridge, Kent C ; Graybiel, Ann M ; Fentress, John C

Nature reviews. Neuroscience, 2016-01, Vol.17 (1), p.45-59 [Periódico revisado por pares]

England: Nature Publishing Group

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Título:
Neurobiology of rodent self-grooming and its value for translational neuroscience
Autor: Kalueff, Allan V ; Stewart, Adam Michael ; Song, Cai ; Berridge, Kent C ; Graybiel, Ann M ; Fentress, John C
Assuntos: Animal cognition ; Animals ; Autism Spectrum Disorder - physiopathology ; Behavior ; Behavior, Animal - physiology ; Brain research ; Disease Models, Animal ; Grooming - physiology ; Grooming behavior in animals ; Humans ; Neurobiology ; Neurosciences ; Obsessive-Compulsive Disorder - genetics ; Obsessive-Compulsive Disorder - physiopathology ; Psychological aspects ; Rodents
É parte de: Nature reviews. Neuroscience, 2016-01, Vol.17 (1), p.45-59
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Descrição: Self-grooming is a complex innate behaviour with an evolutionarily conserved sequencing pattern and is one of the most frequently performed behavioural activities in rodents. In this Review, we discuss the neurobiology of rodent self-grooming, and we highlight studies of rodent models of neuropsychiatric disorders--including models of autism spectrum disorder and obsessive compulsive disorder--that have assessed self-grooming phenotypes. We suggest that rodent self-grooming may be a useful measure of repetitive behaviour in such models, and therefore of value to translational psychiatry. Assessment of rodent self-grooming may also be useful for understanding the neural circuits that are involved in complex sequential patterns of action.
Editor: England: Nature Publishing Group
Idioma: Inglês

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Neurobiology of rodent self-grooming and its value for translational neuroscience

Kalueff, Allan V ; Stewart, Adam Michael ; Song, Cai ; Berridge, Kent C ; Graybiel, Ann M ; Fentress, John C

England: Nature Publishing Group

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