skip to main content
Idioma:

Familial steroid-sensitive idiopathic nephrotic syndrome: seven cases from three families in China

Xia, Yonghui; Mao, Jianhua; Jin, Xia; Wang, Wenjing; Du, Lizhong; Liu, Aimin

Clinics; v. 68 n. 5 (2013); 628-631

Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo 2013-05-01

Acesso online

  • Título:
    Familial steroid-sensitive idiopathic nephrotic syndrome: seven cases from three families in China
  • Autor: Xia, Yonghui; Mao, Jianhua; Jin, Xia; Wang, Wenjing; Du, Lizhong; Liu, Aimin
  • É parte de: Clinics; v. 68 n. 5 (2013); 628-631
  • Descrição: OBJECTIVES: Familial steroid-sensitive idiopathic nephrotic syndrome is rare, and only approximately 3% of patients have affected siblings. METHODS: Herein, we report seven cases of patients with steroid-sensitive idiopathic nephrotic syndrome from three Chinese families. Mutational screening of the Nphs2 gene was performed in all the patients. RESULTS: All seven of the familial steroid-sensitive idiopathic nephrotic syndrome cases in our sample exhibited minimal change disease, and one case also presented with mesangial proliferative glomerulonephritis, according to the renal pathology. No significant was associations were found between Nphs2 gene mutations and the onset of proteinuria and nephrotic syndrome in these familial cases. CONCLUSIONS: The presence of minimal change disease is important, but it is not an unusual finding in patients with familial steroid-sensitive idiopathic nephrotic syndrome, which appears to be clinically benign and genetically distinct from other types of nephrosis.
  • Títulos relacionados: https://www.revistas.usp.br/clinics/article/view/76838/80700
  • Editor: Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
  • Data de criação/publicação: 2013-05-01
  • Formato: Adobe PDF
  • Idioma: Inglês
Links
Voltar para lista de resultados
Ir para página anteriorAnterior Resultado  5 AvançarIr para próxima página

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.