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1,3-Dimethylisoguanine, a New Purine from the Marine Sponge Amphimedon viridis

Chehade, Claire C ; Dias, Ricardo L. A ; Berlinck, Roberto G. S ; Ferreira, Antonio G ; Costa, Letícia V ; Rangel, Marisa ; Malpezzi, Elena L. A ; de Freitas, José Carlos ; Hajdu, Eduardo

Journal of natural products (Washington, D.C.), 1997-07, Vol.60 (7), p.729-731 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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Título:
1,3-Dimethylisoguanine, a New Purine from the Marine Sponge Amphimedon viridis
Autor: Chehade, Claire C ; Dias, Ricardo L. A ; Berlinck, Roberto G. S ; Ferreira, Antonio G ; Costa, Letícia V ; Rangel, Marisa ; Malpezzi, Elena L. A ; de Freitas, José Carlos ; Hajdu, Eduardo
Assuntos: Amphimedon viridis ; Animals ; Biological and medical sciences ; BRASIL ; BRAZIL ; BRESIL ; CHEMICAL COMPOSITION ; CHEMICAL STRUCTURE ; COMPOSICION QUIMICA ; COMPOSITION CHIMIQUE ; DERIVATIVES ; Electric Stimulation ; EPONGE ; ESPECTROMETRIA ; ESPONJAS ; ESTRUCTURA QUIMICA ; General pharmacology ; GUANINA ; GUANINE ; Guanine - analogs & derivatives ; Guanine - chemistry ; Guanine - isolation & purification ; Guanine - pharmacology ; Guinea Pigs ; In Vitro Techniques ; Marine ; Medical sciences ; MUSCLE ; MUSCLE CONTRACTION ; Muscle Contraction - drug effects ; Muscle Contraction - physiology ; MUSCLES ; MUSCULOS ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. Drug treatments ; Porifera ; Porifera - chemistry ; PURINAS ; PURINE ; PURINES ; REGULATION ; SPECTRAL ANALYSIS ; SPECTROMETRIE ; SPECTROMETRY ; SPONGES ; STRUCTURE CHIMIQUE
É parte de: Journal of natural products (Washington, D.C.), 1997-07, Vol.60 (7), p.729-731
Notas: Q60
9741414
L50
M01
istex:3B5C50DA1F5B9DDAF324965F28472781942966BB
Instituto de Biociências, Universidade de São Paulo.
ark:/67375/TPS-48L5CG3Q-1
Abstract published in Advance ACS Abstracts, June 15, 1997.
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: A new purine, 1,3-dimethylisoguanine (1), has been isolated from the marine sponge Amphimedon viridis and identified by analysis of spectroscopic data. Compound 1 increased the contractions obtained by transmural electrical stimulation in the guinea pig longitudinal muscle/myenteric plexus in a dose-dependent manner.
Editor: Washington, DC: American Chemical Society
Idioma: Inglês

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1,3-Dimethylisoguanine, a New Purine from the Marine Sponge Amphimedon viridis

Chehade, Claire C ; Dias, Ricardo L. A ; Berlinck, Roberto G. S ; Ferreira, Antonio G ; Costa, Letícia V ; Rangel, Marisa ; Malpezzi, Elena L. A ; de Freitas, José Carlos ; Hajdu, Eduardo

Washington, DC: American Chemical Society

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