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Platelet-derived growth factor induces rapid but transient expression of the c- fos gene and protein

Kruijer, Wiebe ; Cooper, Jonathan A ; Hunter, Tony ; Verma, Inder M

Nature (London), 1984-01, Vol.312 (5996), p.711-716 [Periódico revisado por pares]

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Título:
Platelet-derived growth factor induces rapid but transient expression of the c- fos gene and protein
Autor: Kruijer, Wiebe ; Cooper, Jonathan A ; Hunter, Tony ; Verma, Inder M
Assuntos: Animals ; Biological and medical sciences ; Cell physiology ; Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes ; Fibroblasts ; Fundamental and applied biological sciences. Psychology ; Gene Expression Regulation - drug effects ; genes ; Mice ; Mitogens - pharmacology ; Mitosis ; Molecular and cellular biology ; Oncogenes ; platelet-derived growth factor ; Platelet-Derived Growth Factor - pharmacology ; Protein Processing, Post-Translational ; RNA, Messenger - genetics ; transcription ; Transcription, Genetic
É parte de: Nature (London), 1984-01, Vol.312 (5996), p.711-716
Notas: ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 23
ObjectType-Article-1
ObjectType-Feature-2
Descrição: Exposure of quiescent mouse fibroblasts to platelet-derived growth factor induces mRNA from the c-fos proto-oncogene within 10 min followed by synthesis of nuclear c-fos proteins. These are amongst the earliest described nuclear events that follow a mitogenic stimulus.
Editor: London: Nature Publishing
Idioma: Inglês

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