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Size at Birth, Infant Growth, and Blood Pressure at Three Years of Age

Belfort, Mandy B., MD, MPH ; Rifas-Shiman, Sheryl L., MPH ; Rich-Edwards, Janet, ScD ; Kleinman, Ken P., ScD ; Gillman, Matthew W., MD, SM

The Journal of pediatrics, 2007-12, Vol.151 (6), p.670-674 [Periódico revisado por pares]

New York, NY: Mosby, Inc

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Título:
Size at Birth, Infant Growth, and Blood Pressure at Three Years of Age
Autor: Belfort, Mandy B., MD, MPH ; Rifas-Shiman, Sheryl L., MPH ; Rich-Edwards, Janet, ScD ; Kleinman, Ken P., ScD ; Gillman, Matthew W., MD, SM
Assuntos: Biological and medical sciences ; Birth Weight - physiology ; Blood Pressure ; Body Height ; Body Mass Index ; Child, Preschool ; Cohort Studies ; General aspects ; Growth - physiology ; Humans ; Infant ; Infant, Newborn - growth & development ; Medical sciences ; Pediatrics ; Weight Gain - physiology
É parte de: The Journal of pediatrics, 2007-12, Vol.151 (6), p.670-674
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Descrição: Objectives Our aim was to determine the extent to which infant growth—in weight-for-length—from birth to 6 months is associated with systolic blood pressure (SBP) at 3 years and to determine whether this association varies with birth size. Study design In 530 children from the prospective cohort Project Viva, we measured birth length and 6-month weight and length with research standard instruments and SBP at age 3 years with a Dinamap automated recorder. We derived weight-for-length z-scores (WFL-z) and analyzed data with mixed effects regression models. Results The mean (SD) WFL-z was 0.47 (0.75) at birth and 0.70 (0.96) at 6 months. Mean (SD) SBP at 3 years was 91.7 (9.4) mm Hg. After adjusting for confounding variables and birth WFL-z, child SBP was 1.0 mm Hg (95% CI 0.2, 1.8) higher for each z-score increment in 6-month WFL-z. The SBP of children in the lowest birth WFL-z quartile and the highest 6-month WFL-z quartile was 5.5 mm Hg (95% CI 2.6, 8.4) higher than that of children in the highest birth and lowest 6-month WFL-z quartiles. Conclusions More rapid increase in weight-for-length, a measure of adiposity, in the first 6 months of life is associated with higher early childhood SBP, particularly in children who are thin at birth.
Editor: New York, NY: Mosby, Inc
Idioma: Inglês

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Size at Birth, Infant Growth, and Blood Pressure at Three Years of Age

Belfort, Mandy B., MD, MPH ; Rifas-Shiman, Sheryl L., MPH ; Rich-Edwards, Janet, ScD ; Kleinman, Ken P., ScD ; Gillman, Matthew W., MD, SM

New York, NY: Mosby, Inc

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