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Efficacy of Brazilian propolis gel for the management of denture stomatitis: a pilot study

Santos, Vagner R ; Gomes, Rafael T ; Mesquita, Ricardo A. de ; Moura, Mariela D.G. de ; França, Esdras C ; Aguiar, Evandro G. de ; Naves, Marcelo D ; Abreu, José A.S ; Abreu, Sheila R.L

Phytotherapy research, 2008-11, Vol.22 (11), p.1544-1547 [Periódico revisado por pares]

Chichester, UK: John Wiley & Sons, Ltd

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Título:
Efficacy of Brazilian propolis gel for the management of denture stomatitis: a pilot study
Autor: Santos, Vagner R ; Gomes, Rafael T ; Mesquita, Ricardo A. de ; Moura, Mariela D.G. de ; França, Esdras C ; Aguiar, Evandro G. de ; Naves, Marcelo D ; Abreu, José A.S ; Abreu, Sheila R.L
Assuntos: Administration, Topical ; Adult ; Aged ; Animals ; Antifungal Agents - therapeutic use ; Biological and medical sciences ; Candida albicans - drug effects ; Candidiasis, Oral - drug therapy ; denture stomatitis ; Denture, Complete - adverse effects ; Female ; gel ; Gels ; General pharmacology ; Humans ; Male ; Medical sciences ; miconazole ; Miconazole - therapeutic use ; Middle Aged ; Mouth Mucosa - microbiology ; Pharmacognosy. Homeopathy. Health food ; Pharmacology. Drug treatments ; Pilot Projects ; propolis ; Propolis - therapeutic use ; Stomatitis, Denture - drug therapy
É parte de: Phytotherapy research, 2008-11, Vol.22 (11), p.1544-1547
Notas: http://dx.doi.org/10.1002/ptr.2541
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SourceType-Scholarly Journals-1
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Descrição: Denture stomatitis presents as a chronic disease in denture-bearing patients, especially under maxillary prosthesis. Despite the existence of a great number of antifungal agents, treatment failure is observed frequently. Propolis, a natural bee product, possesses well-documented antifungal and anti-inflammatory activities. The purpose of this study was to evaluate the clinical efficacy of a new Brazilian propolis gel formulation in patients diagnosed with denture stomatitis. Thirty complete-denture wearers with denture stomatitis were enrolled in this pilot study. At baseline, clinical evaluation was performed by a single clinician and instructions for denture hygiene were provided. Fifteen patients received Daktarin® (Miconazole gel) and 15 received Brazilian propolis gel. All patients were recommended to apply the product four times a day during one week. Clinical evaluation was repeated by the same clinician after treatment. All patients treated with Brazilian propolis gel and Daktarin® had complete clinical remission of palatal edema and erythema. This new Brazilian propolis gel formulation had efficacy comparable to Daktarin® and could be an alternative topical choice for the treatment of denture stomatitis. Copyright © 2008 John Wiley & Sons, Ltd.
Editor: Chichester, UK: John Wiley & Sons, Ltd
Idioma: Inglês

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Efficacy of Brazilian propolis gel for the management of denture stomatitis: a pilot study

Santos, Vagner R ; Gomes, Rafael T ; Mesquita, Ricardo A. de ; Moura, Mariela D.G. de ; França, Esdras C ; Aguiar, Evandro G. de ; Naves, Marcelo D ; Abreu, José A.S ; Abreu, Sheila R.L

Chichester, UK: John Wiley & Sons, Ltd

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