Idioma:

Proposed Classification of the Feline “Complex” Mammary Tumors as Ductal and Intraductal Papillary Mammary Tumors

Zappulli, V. ; Caliari, D. ; Rasotto, R. ; Ferro, S. ; Castagnaro, M. ; Goldschmidt, M.

Veterinary pathology, 2013-11, Vol.50 (6), p.1070-1077 [Periódico revisado por pares]

Los Angeles, CA: SAGE Publications

Texto completo disponível

Citações Citado por

Enviar para

Título:
Proposed Classification of the Feline “Complex” Mammary Tumors as Ductal and Intraductal Papillary Mammary Tumors
Autor: Zappulli, V. ; Caliari, D. ; Rasotto, R. ; Ferro, S. ; Castagnaro, M. ; Goldschmidt, M.
Assuntos: Animals ; Carcinoma, Ductal - classification ; Carcinoma, Ductal - pathology ; Carcinoma, Ductal - veterinary ; Carcinoma, Intraductal, Noninfiltrating - classification ; Carcinoma, Intraductal, Noninfiltrating - pathology ; Carcinoma, Intraductal, Noninfiltrating - veterinary ; Cat Diseases - classification ; Cat Diseases - pathology ; Cats ; Epithelial Cells - pathology ; Female ; Immunohistochemistry - veterinary ; Mammary Glands, Animal - pathology ; Mammary Neoplasms, Animal - classification ; Mammary Neoplasms, Animal - pathology
É parte de: Veterinary pathology, 2013-11, Vol.50 (6), p.1070-1077
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: When compared with the canine species, feline mammary tumors (FMTs) are much less heterogeneous, with a predominance of simple malignant neoplasm. Benign FMTs are rare, and it is unclear if complex and mixed tumors exist in the feline. In this study, we selected for immunohistochemical analyses 12 FMTs that had unusual histologic features. A group of 8 (2 benign and 6 malignant) FMTs showed a biphasic epithelial/myoepithelial population and a very regular cord-like distribution in a “Chinese lettering” pattern, within ectatic ducts. A second group (2 benign and 2 malignant) had an intraductal epithelial papillary growth pattern with a basally located monolayer of myoepithelial cells and a supporting fibrovascular stroma. The myoepithelial component always produced a standard immunohistochemical signature. All malignancies were grade I, and the subjects were all alive at 1 year postdiagnosis. On the basis of their morphology, we propose that they be classified as feline ductal adenoma/carcinoma and feline intraductal papillary adenoma/carcinoma, respectively. They overlap with their canine counterparts and lack the typical myoepithelial differentiation patterns seen in canine complex neoplasms, and therefore, the term complex should be avoided in felines. This study will add new information on FMT classification and be useful for prognostic studies.
Editor: Los Angeles, CA: SAGE Publications
Idioma: Inglês

Links

View this record in MEDLINE/PubMed

Voltar para lista de resultados

Realização: Logos de Redes Sociais:

Proposed Classification of the Feline “Complex” Mammary Tumors as Ductal and Intraductal Papillary Mammary Tumors

Zappulli, V. ; Caliari, D. ; Rasotto, R. ; Ferro, S. ; Castagnaro, M. ; Goldschmidt, M.

Los Angeles, CA: SAGE Publications

Buscando em bases de dados remotas. Favor aguardar.