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RNA viruses host gene responses to infections

Decheng Yang; World Scientific (Firm)

Singapore World Scientific Pub. Co. Hackensack, N.J. c2009

Acesso online. A biblioteca também possui exemplares impressos.

  • Título:
    RNA viruses host gene responses to infections
  • Autor: Decheng Yang; World Scientific (Firm)
  • Assuntos: RNA viruses; Viral genetics; REGULAÇÃO GÊNICA; EXPRESSÃO GÊNICA; RNA VIRAL (FISIOLOGIA GENÉTICA); VIROSES; GENES VIRAIS; Electronic books
  • Notas: Includes bibliographical references and index.
  • Notas Locais: ICB - Obra adquirida através do Projeto - FAPESP - FAPLIV - VI
  • Descrição: section I. Retrovirus. 1. Efforts to characterize host response to HIV-1 infection / Monty Montano & Paola Sebastiani. 2. Signaling pathways activated by HIV and their impact on immune responses / Katrina Gee ... [et al.]. 3. Host immune responses in HIV infection / Robert D. Allison & Shyam Kottilil. 4. HIV-1 and RNA interference -- examining a complex system / Zachary A. Klase, Kuan-Teh Jeang & Fatah Kashanchi -- section II. Negative single-stranded RNA virus. 5. Signaling pathways induced by influenza viruses / Stephan Pleschka ... [et al.]. 6. Host immune response to influenza virus / Thomas M. Moran & Carolina B. López. 7. Signaling pathways in the host cell response to RSV infection / Allan R. Brasier ... [et al.]. 8. Protective and pathologic host responses to pulmonary respiratory syncytial virus infection / Dennis M. Lindell & Nicholas W. Lukacs. 9. Innate recognition of viral infection and the involvement of autophagy / Balaji Ramanathan & Akiko Iwasaki. 10. VSV infection elicits distinct host responses in the periphery and the brain / Carol Shoshkes Reiss. 11. Hantavirus infection and innate immunity / Nandini Sen ... [et al.]. 12. Measles virus captures specific host machineries to cause immunosuppression and disease / Bumsuk Hahm & Michael B.A. Oldstone -- section III. Positive single-stranded RNA virus. 13. Severe acute respiratory syndrome coronavirus induces differential host gene expression responses associated with pathogenesis / Vincent T.K. Chow & W.F. Leong. 14. Characterization of signaling pathways in cells infected with SARS-CoV / Tetsuya Mizutani. 15. Impact of filovirus infection upon cellular signaling pathways / Christopher F. Basler. 16. Responses to Ebola and Marburg virus infections / Thomas W. Geisbert ... [et al.]. 17. Host gene expression triggered by West Nile virus infection / Janusz T. Pawùeska. 18. West Nile virus-host interaction : an immunological prospective / Raghavan Bhuvanakantham & Mah-Lee Ng. 19. Hepatitis
    This is the first comprehensive book on human/animal gene responses to RNA viral infections, including prevalent, emerging and re-emerging RNA viruses such as HIV, SARS-CoV, West Nile virus, influenza virus and many others. Human gene responses are reviewed by leading virologists worldwide in the following aspects: (i) the altered gene expression profiles at the transcriptional and translational levels detected with cutting-edge technologies such as cDNA microarray and proteomics; (ii) host innate and adapted immune responses to viral replication in target organs; (iii) virus-activated signal transduction pathways in cell survival, apoptosis and autophagosomal pathways; and (iv) the small interfering RNA/microRNA-mediated gene silencing pathway, a recently characterized new host defense mechanism against viral infection. Organized into 27 highly accessible and well-illustrated chapters, this volume explores state-of-the-art knowledge of the molecular mechanisms of RNA virus infection and hostb6svirus interactions. This comprehensive compilation of the altered gene expression profiles and signal transduction pathways in host cells in response to the majority of human/animal RNA viruses opens new directions for basic and clinical research on viral pathogenesis, and also provides valuable biomarkers for researchers to select gene targets in the development of diagnostic tests and antiviral therapeutics for a number of infectious diseases.
  • Editor: Singapore World Scientific Pub. Co. Hackensack, N.J.
  • Data de criação/publicação: c2009
  • Formato: xxx, 691 p ill. (some col.), col. map..
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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