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Sahlgrenska University Hospital - a Nordic center for clinical UTx in the future?

Brännström, Mats

Läkartidningen, 2022-12, Vol.119 [Periódico revisado por pares]

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Título:
Sahlgrenska University Hospital - a Nordic center for clinical UTx in the future?
Autor: Brännström, Mats
Assuntos: Animals ; Female ; Hospitals ; Humans ; Infertility, Female - surgery ; Live Birth ; Living Donors ; Pregnancy ; Uterus - surgery
É parte de: Läkartidningen, 2022-12, Vol.119
Descrição: Absolute uterine factor infertility was regarded as untreatable until the introduction of human uterus transplantation (UTx), with the proof-of-concept being the first live birth in 2014. Our research project on UTx started already in 1999, with systematic research in several animal models for more than a decade. The first clinical UTx study was initiated in Sweden in 2012 and included nine live-donor UTx procedures, by laparotomy in donor and recipient. Seven procedures were surgically successful and a total of nine live births occurred between 2014 and 2020. A large number of research studies on several aspects and outcomes of the study have been published. Presently, studies are conducted to develop robotic-assisted laparoscopy for surgery on live donor and recipient. Moreover, a laboratory-based project explores the possibility to create a bioengineered uterus. We hope that Sahlgrenska University Hospital can become a Nordic center for clinical UTx in the future.
Editor: Sweden
Idioma: Sueco

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