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Epidemiology of MS

Bohlega, Saeed

Multiple sclerosis and related disorders, 2014-11, Vol.3 (6), p.766-767

Elsevier B.V

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  • Título:
    Epidemiology of MS
  • Autor: Bohlega, Saeed
  • Assuntos: Neurology
  • É parte de: Multiple sclerosis and related disorders, 2014-11, Vol.3 (6), p.766-767
  • Descrição: Multiple sclerosis (MS) is reported globally and is the most common cause of neurological disability in young adults. Comparisons of the incidence and prevalence of disease among different populations and ethnic groups confirm that both genetic and environmental factors contribute to MS etiology. Scarce reports published in the Middle East and North Africa but recent data indicate that the prevalence of MS is strikingly increasing in these regions. The findings of many meta-analyses suggest that the incidence of MS has increased over time and provide some evidence that this is due primarily to an increase in rates of MS among women. When reviewing such epidemiological studies, study duration and diagnostic criteria applied are the two most important factors to take into account before forming conclusions. Another factor is that, in the past, comparisons between studies have lacked the appropriate standardization. However, the most recently reported analyses generally had high-quality scores. Such studies have suggested the following additional factors that might be linked to the increase in MS prevalence: the reporting of cases in the early stages of disease, access to neurological care centers, the availability of magnetic resonance imaging, and the use of disease-modifying therapies. Available MS treatments have increased the life expectancy of individual patients and changed the natural history of the disease worldwide. The noted increase in the prevalence and incidence of MS in different ethnic groups is likely to be a multifactorial phenomenon. Several of these factors have been described, including genetic background and environment, infections, status of self-immunity, travel across continents, and alteration of vitamin D and calcium levels in the different communities and among patients; other reasons are yet to be elucidated.
  • Editor: Elsevier B.V
  • Idioma: Inglês
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  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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