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CT and MRI fusion for postimplant prostate brachytherapy evaluation

Dehghan, Ehsan ; Yi Le ; Junghoon Lee ; Song, Daniel Y. ; Fichtinger, Gabor ; Prince, Jerry L.

2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI), 2016-04, Vol.2016, p.625-628

United States: IEEE

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  • Título:
    CT and MRI fusion for postimplant prostate brachytherapy evaluation
  • Autor: Dehghan, Ehsan ; Yi Le ; Junghoon Lee ; Song, Daniel Y. ; Fichtinger, Gabor ; Prince, Jerry L.
  • Assuntos: Brachytherapy ; Computed tomography ; Dosimetry ; Image reconstruction ; Magnetic resonance imaging ; Manuals ; MRI ; Multi-Modality Registration ; Prostate Brachytherapy
  • É parte de: 2016 IEEE 13th International Symposium on Biomedical Imaging (ISBI), 2016-04, Vol.2016, p.625-628
  • Descrição: Postoperative evaluation of prostate brachytherapy is typically performed using CT, which does not have sufficient soft tissue contrast for accurate anatomy delineation. MR-CT fusion enables more accurate localization of both anatomy and implanted radioactive seeds, and hence, improves the accuracy of postoperative dosimetry. We propose a method for automatic registration of MR and CT images without a need for manual initialization. Our registration method employs a point-to-volume registration scheme during which localized seeds in the CT images, produced by commercial treatment planning systems as part of the standard of care, are rigidly registered to preprocessed MRI images. We tested our algorithm on ten patient data sets and achieved an overall registration error of 1.6 ± 0.8 mm with a running time of less than 20s. With high registration accuracy and computational speed, and no need for manual intervention, our method has the potential to be employed in clinical applications.
  • Editor: United States: IEEE
  • Idioma: Inglês
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